NFKBIA anticorps (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha) (pTyr42) (FITC)

Details for Product anti-NFKBIA Antibody No. ABIN710688
Antigène
  • IKBA
  • MAD-3
  • NFKBI
  • AI462015
  • Nfkbi
  • RL/IF-1
  • ECI-6/IKBA
  • ikbaA
  • wu:fj16a07
  • zgc:85769
  • NFKB inhibitor alpha
  • nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a
  • NFKBIA
  • Nfkbia
  • nfkbiaa
Épitope
pTyr42
63
54
40
35
35
18
17
15
15
12
10
10
8
7
7
5
5
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris
485
307
248
31
24
20
19
9
2
2
2
1
1
Hôte
Lapin
429
62
7
7
Clonalité
Polyclonal
Conjugué
Cet anticorp NFKBIA est conjugé à/à la FITC
26
13
13
13
13
13
13
12
9
6
6
6
3
3
3
3
3
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
364
182
159
78
77
62
40
28
19
17
16
4
4
3
3
3
1
1
1
Options
Immunogène KLH conjugated synthetic phosphopeptide derived from human IKB alpha around the phosphorylation site of Tyr42
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others NFKBIA products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation Nfkbia (NFKBIA Antibody Extrait)
Sujet

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011].

Synonyms: NFKBIATyr42, NFKBIAphospho Y42, IKB-alphaTyr42, IKB alpha, Inhibitor of KB alpha, I kappa B alpha, IKappaBalpha, IkappaBalpha, IKBA, IKBalpha, MAD 3, MAD3, Major histocompatibility complex enhancer binding protein MAD3, NF kappa B inhibitor alpha, NFKBI, NFKBIA, Nuclear factor of kappa light chain gene enhancer in B cells, Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor alpha.

ID gène 4792
Pathways Signalisation NF-kappaB, TCR Signaling, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Maintenance of Protein Location, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades
Indications d'application IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
Avez-vous cherché autre chose?