CYP3A4 anticorps (AA 259-441)

N° du produit ABIN7149259

Détail du produit anti-CYP3A4 anticorps

Antigène: CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))

Épitope: AA 259-441

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP3A4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Cytochrome P450 3A4 protein (259-441AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:200-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CYP3A4

Antigène: CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))

Autre désignation: CYP3A4 (CYP3A4 Produits)

Synonymes: anticorps CP33, anticorps CP34, anticorps CYP3A, anticorps CYP3A3, anticorps CYPIIIA3, anticorps CYPIIIA4, anticorps HLP, anticorps NF-25, anticorps P450C3, anticorps P450PCN1, anticorps MGC108372, anticorps CYP3A80, anticorps CYP3A4, anticorps CYP3A21, anticorps CYPIIIA21, anticorps CYP3A12, anticorps cytochrome P450 family 3 subfamily A member 4, anticorps cytochrome P450 family 3 subfamily A member 43, anticorps cytochrome P450 3A4, anticorps cytochrome P450, subfamily IIIA, polypeptide 4, anticorps cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4, anticorps cytochrome P450, family 3, subfamily A, polypeptide 4, anticorps CYP3A4, anticorps CYP3A43, anticorps PTRG_01782, anticorps PTRG_06060, anticorps cyp3a4

Sujet:

Background: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1\\\'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2-exo-monooxygenase. The enzyme also hydroxylates etoposide (PubMed:11159812). Catalyzes 4-beta-hydroxylation of cholesterol. May catalyze 25-hydroxylation of cholesterol in vitro (PubMed:21576599).

Aliases: 1,8-cineole 2-exo-monooxygenase antibody, Albendazole monooxygenase antibody, Albendazole sulfoxidase antibody, CP33 antibody, CP34 antibody, CP3A4_HUMAN antibody, CYP3 antibody, CYP3A antibody, CYP3A3 antibody, CYP3A4 antibody, CYPIIIA3 antibody, CYPIIIA4 antibody, Cytochrome P450 3A3 antibody, Cytochrome P450 3A4 antibody, Cytochrome P450 family 3 subfamily A polypeptide 4 antibody, Cytochrome P450 HLp antibody, Cytochrome P450 NF-25 antibody, Cytochrome P450 subfamily IIIA polypeptide 4 antibody, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3 antibody, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 antibody, Cytochrome P450-PCN1 antibody, Glucocorticoid inducible P450 antibody, HLP antibody, MGC126680 antibody, NF 25 antibody, NF25 antibody, Nifedipine oxidase antibody, P450 III steroid inducible antibody, P450 PCN1 antibody, P450, family III antibody, P450C3 antibody, P450PCN1 antibody, Quinine 3 monooxygenase antibody, Quinine 3-monooxygenase antibody, Taurochenodeoxycholate 6 alpha hydroxylase antibody, Taurochenodeoxycholate 6-alpha-hydroxylase antibody

UniProt: P08684

Pathways: Steroid Hormone Biosynthesis