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DNAJC2 anticorps (AA 1-140)

DNAJC2 Reactivité: Humain ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7150549
  • Antigène Voir toutes DNAJC2 Anticorps
    DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))
    Épitope
    • 7
    • 7
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-140
    Reactivité
    • 31
    • 20
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 30
    • 2
    Lapin
    Clonalité
    • 30
    • 2
    Polyclonal
    Conjugué
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DNAJC2 est non-conjugé
    Application
    • 24
    • 17
    • 4
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
     Réactivité croisée
    Humain
    Purification
    Antigen Affinity Purified
    Immunogène
    Recombinant Human DnaJ homolog subfamily C member 2 protein (1-140AA)
    Isotype
    IgG
    Top Product
    Discover our top product DNAJC2 Anticorps primaire
  • Indications d'application
    Recommended dilution: IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))
    Autre désignation
    DNAJC2 (DNAJC2 Produits)
    Synonymes
    anticorps zrf1, anticorps ZRF1, anticorps MPHOSPH11, anticorps MPP11, anticorps ZUO1, anticorps AU020218, anticorps MIDA1, anticorps Zrf1, anticorps Zrf2, anticorps zgc:85671, anticorps DnaJ heat shock protein family (Hsp40) member C2, anticorps DnaJ (Hsp40) homolog, subfamily C, member 2, anticorps dnajc2, anticorps DNAJC2, anticorps Dnajc2
    Sujet

    Background: Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at \\\'Lys-119\\\' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation. Specifically binds DNA sequence 5\\\'-GTCAAGC-3\\\'.

    Aliases: AU020218 antibody, DnaJ (Hsp40) homolog subfamily C member 2 antibody, DnaJ homolog subfamily C member 2 antibody, Dnajc2 antibody, DNJC2_HUMAN antibody, M phase phosphoprotein 11 antibody, M-phase phosphoprotein 11 antibody, MGC105894 antibody, MIDA1 antibody, MPHOSPH11 antibody, MPP11 antibody, OTTMUSP00000031226 antibody, ZRF1 antibody, Zrf2 antibody, ZUO1 antibody, Zuotin related factor 1 antibody, Zuotin related factor 2 antibody, Zuotin-related factor 1 antibody

    UniProt
    Q99543
    Pathways
    Chromatin Binding
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