DNAJC2 anticorps (AA 1-140)
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- Antigène Voir toutes DNAJC2 Anticorps
- DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))
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Épitope
- AA 1-140
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DNAJC2 est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC)
- Réactivité croisée
- Humain
- Purification
- Antigen Affinity Purified
- Immunogène
- Recombinant Human DnaJ homolog subfamily C member 2 protein (1-140AA)
- Isotype
- IgG
- Top Product
- Discover our top product DNAJC2 Anticorps primaire
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- Indications d'application
- Recommended dilution: IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))
- Autre désignation
- DNAJC2 (DNAJC2 Produits)
- Synonymes
- anticorps zrf1, anticorps ZRF1, anticorps MPHOSPH11, anticorps MPP11, anticorps ZUO1, anticorps AU020218, anticorps MIDA1, anticorps Zrf1, anticorps Zrf2, anticorps zgc:85671, anticorps DnaJ heat shock protein family (Hsp40) member C2, anticorps DnaJ (Hsp40) homolog, subfamily C, member 2, anticorps dnajc2, anticorps DNAJC2, anticorps Dnajc2
- Sujet
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Background: Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at \\\'Lys-119\\\' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation. Specifically binds DNA sequence 5\\\'-GTCAAGC-3\\\'.
Aliases: AU020218 antibody, DnaJ (Hsp40) homolog subfamily C member 2 antibody, DnaJ homolog subfamily C member 2 antibody, Dnajc2 antibody, DNJC2_HUMAN antibody, M phase phosphoprotein 11 antibody, M-phase phosphoprotein 11 antibody, MGC105894 antibody, MIDA1 antibody, MPHOSPH11 antibody, MPP11 antibody, OTTMUSP00000031226 antibody, ZRF1 antibody, Zrf2 antibody, ZUO1 antibody, Zuotin related factor 1 antibody, Zuotin related factor 2 antibody, Zuotin-related factor 1 antibody
- UniProt
- Q99543
- Pathways
- Chromatin Binding
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