MS4A2 anticorps (AA 1-59) (FITC)

N° du produit ABIN7155186

Détail du produit anti-MS4A2 anticorps (FITC)

Antigène: MS4A2 (Membrane-Spanning 4-Domains, Subfamily A, Member 2 (Fc Fragment of IgE, High Affinity I, Receptor For, beta Polypeptide) (MS4A2))

Épitope: AA 1-59

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MS4A2 est conjugé à/à la FITC

Application: Veuillez nous consulter SVP

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human High affinity immunoglobulin epsilon receptor subunit beta protein (1-59AA)

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MS4A2

Antigène: MS4A2 (Membrane-Spanning 4-Domains, Subfamily A, Member 2 (Fc Fragment of IgE, High Affinity I, Receptor For, beta Polypeptide) (MS4A2))

Autre désignation: MS4A2 (MS4A2 Produits)

Synonymes: anticorps APY, anticorps ATOPY, anticorps FCER1B, anticorps FCERI, anticorps IGEL, anticorps IGER, anticorps IGHER, anticorps MS4A1, anticorps FcRB, anticorps Fce1b, anticorps Fcer1b, anticorps Fcrbeta, anticorps Ms4a1, anticorps fcERI, anticorps FCIGA, anticorps membrane spanning 4-domains A2, anticorps membrane-spanning 4-domains, subfamily A, member 2, anticorps MS4A2, anticorps Ms4a2

Sujet:

Background: High affinity receptor that binds to the Fc region of immunoglobulins epsilon. Aggregation of FCER1 by multivalent antigens is required for the full mast cell response, including the release of preformed mediators (such as histamine) by degranulation and de novo production of lipid mediators and cytokines. Also mediates the secretion of important lymphokines. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators responsible for the manifestations of allergy.

Aliases: APY antibody, ATOPY antibody, Fc epsilon receptor I beta-chain antibody, Fc IgE receptor beta chain antibody, FCER1B antibody, FCERB_HUMAN antibody, FcERI antibody, High affinity immunoglobulin epsilon receptor subunit beta antibody, IgE Fc receptor subunit beta antibody, IGEL antibody, IGHER antibody, Membrane-spanning 4-domains subfamily A member 2 antibody, MS4A1 antibody, Ms4a2 antibody

UniProt: Q01362

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process