ITPR1 anticorps (AA 1707-1966)

N° du produit ABIN7156293

Détail du produit anti-ITPR1 anticorps

Antigène: ITPR1 (Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1))

Épitope: AA 1707-1966

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITPR1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Inositol 1,4,5-trisphosphate receptor type 1 protein (1707-1966AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ITPR1

Antigène: ITPR1 (Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1))

Autre désignation: ITPR1 (ITPR1 Produits)

Synonymes: anticorps D6Pas2, anticorps ENSMUSG00000072853, anticorps Gm10429, anticorps IP3R1, anticorps InsP3R, anticorps Ip3r, anticorps Itpr-1, anticorps P400, anticorps Pcp-1, anticorps Pcp1, anticorps opt, anticorps I145TR, anticorps InsP3R1, anticorps INSP3R1, anticorps IP3R, anticorps SCA15, anticorps SCA16, anticorps SCA29, anticorps inositol 1,4,5-trisphosphate receptor type 1, anticorps inositol 1,4,5-trisphosphate receptor 1, anticorps inositol 1,4,5-trisphosphate receptor, type 1, anticorps ITPR1, anticorps Itpr1

Sujet:

Background: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate (PubMed:27108797). Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1 (By similarity). Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).

Aliases: 4 antibody, 5-trisphosphate receptor antibody, 5-trisphosphate receptor type 1 antibody, DKFZp313E1334 antibody, DKFZp313N1434 antibody, inositol 1 4 5 triphosphate receptor type 1 antibody, Inositol 1 4 5 trisphosphate Receptor Type 1 antibody, Inositol 1 antibody, InsP3R1 antibody, IP3 antibody, IP3 receptor antibody, IP3 receptor isoform 1 antibody, IP3R 1 antibody, IP3R antibody, IP3R1 antibody, ITPR 1 antibody, Itpr1 antibody, ITPR1_HUMAN antibody, SCA15 antibody, SCA16 antibody, SCA29 antibody, Type 1 inositol 1 4 5 trisphosphate receptor antibody, Type 1 inositol 1 antibody, Type 1 InsP3 receptor antibody

UniProt: Q14643

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, Synaptic Membrane, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma