KHDRBS2 anticorps (AA 1-349)

N° du produit ABIN7157478

Détail du produit anti-KHDRBS2 anticorps

Antigène: KHDRBS2 (KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2))

Épitope: AA 1-349

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KHDRBS2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human KH domain-containing, RNA-binding, signal transduction-associated protein 2 protein (1-349AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur KHDRBS2

Antigène: KHDRBS2 (KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2))

Autre désignation: KHDRBS2 (KHDRBS2 Produits)

Synonymes: anticorps slm1, anticorps slm-1, anticorps MGC145973, anticorps ba535f17.1, anticorps zgc:153588, anticorps SLM-1, anticorps SLM1, anticorps bA535F17.1, anticorps 6330586C16Rik, anticorps Slim1, anticorps Slm1, anticorps KH RNA binding domain containing, signal transduction associated 2, anticorps KH domain containing, RNA binding, signal transduction associated 2, anticorps KHDRBS2, anticorps khdrbs2, anticorps Khdrbs2

Sujet:

Background: RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability (By similarity). Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. Can regulate alternative splicing of NRXN1 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4) involved in neurexin selective targeting to postsynaptic partners. Regulates cell-type specific alternative splicing of NRXN1 at AS4 and acts synergystically with SAM68 in exon skipping. In contrast acts antagonistically with SAM68 in NRXN3 exon skipping at AS4. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. May function as an adapter protein for Src kinases during mitosis.

Aliases: KH domain containing, RNA binding, signal transduction associated protein 2 antibody, 6330586C16Rik antibody, bA535F17.1 antibody, FLJ38664 antibody, hSLM 1 antibody, hSLM-1 antibody, KH domain containing, RNA binding, signal transduction associated 2 antibody, KH domain-containing antibody, KHDR2_HUMAN antibody, khdrbs2 antibody, MGC26664 antibody, RNA-binding antibody, Sam68 like mammalian protein 1 antibody, Sam68-like mammalian protein 1 antibody, signal transduction-associated protein 2 antibody, SLM 1 antibody, SLM-1 antibody, SLM1 antibody

UniProt: Q5VWX1