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ZC3HC1 anticorps (AA 1-260)

ZC3HC1 Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7161952
  • Antigène Voir toutes ZC3HC1 Anticorps
    ZC3HC1 (Zinc Finger, C3HC-Type Containing 1 (ZC3HC1))
    Épitope
    • 18
    • 15
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-260
    Reactivité
    • 47
    • 23
    • 20
    • 6
    Humain
    Hôte
    • 47
    Lapin
    Clonalité
    • 47
    Polyclonal
    Conjugué
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp ZC3HC1 est non-conjugé
    Application
    • 31
    • 18
    • 13
    • 13
    • 11
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
     Réactivité croisée
    Humain
    Purification
    Antigen Affinity Purified
    Immunogène
    Recombinant Human Nuclear-interacting partner of ALK protein (1-260AA)
    Isotype
    IgG
  • Indications d'application
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    ZC3HC1 (Zinc Finger, C3HC-Type Containing 1 (ZC3HC1))
    Autre désignation
    ZC3HC1 (ZC3HC1 Produits)
    Synonymes
    anticorps 1110054L24Rik, anticorps AU018540, anticorps AU019789, anticorps HSPC216, anticorps Nipa, anticorps NIPA, anticorps RGD1561099, anticorps zinc finger, C3HC type 1, anticorps zinc finger C3HC-type containing 1, anticorps zinc finger, C3HC-type containing 1, anticorps Zc3hc1, anticorps ZC3HC1
    Sujet

    Background: Essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events.

    Aliases: hNIPA antibody, NIPA_HUMAN antibody, Nuclear interacting partner of ALK antibody, Nuclear interacting partner of anaplastic lymphoma kinase antibody, Nuclear-interacting partner of ALK antibody, Nuclear-interacting partner of anaplastic lymphoma kinase antibody, zc3hc1 antibody, Zinc finger C3HC type containing 1 antibody, Zinc finger C3HC-type protein 1 antibody

    UniProt
    Q86WB0
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