PLA2G2A anticorps (AA 21-144) (Biotin)

N° du produit ABIN7163322

Détail du produit anti-PLA2G2A anticorps (Biotin)

Antigène: PLA2G2A (Phospholipase A2, Group IIA (Platelets, Synovial Fluid) (PLA2G2A))

Épitope: AA 21-144

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLA2G2A est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Phospholipase A2, membrane associated protein (21-144AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PLA2G2A

Antigène: PLA2G2A (Phospholipase A2, Group IIA (Platelets, Synovial Fluid) (PLA2G2A))

Autre désignation: PLA2G2A (PLA2G2A Produits)

Synonymes: anticorps MOM1, anticorps PLA2, anticorps PLA2B, anticorps PLA2L, anticorps PLA2S, anticorps PLAS1, anticorps sPLA2, anticorps EF, anticorps Mom1, anticorps Pla2, anticorps sPla2-IIA, anticorps phospholipase A2 group IIA, anticorps phospholipase A2, group IIA (platelets, synovial fluid), anticorps PLA2G2A, anticorps Pla2g2a

Sujet:

Background: Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (PubMed:2925633). Thought to participate in the regulation of phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Independent of its catalytic activity, acts as a ligand for integrins (PubMed:18635536, PubMed:25398877). Binds to and activates integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1 (PubMed:18635536, PubMed:25398877). Binds to a site (site 2) which is distinct from the classical ligand-binding site (site 1) and induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:25398877). Induces cell proliferation in an integrin-dependent manner (PubMed:18635536).

Aliases: EC 3.1.1.4 antibody, GIIC sPLA2 antibody, Group IIA phospholipase A2 antibody, membrane associated antibody, Modifier of MIN 1 mouse homolog antibody, MOM1 antibody, Non-pancreatic secretory phospholipase A2 antibody, NPS PLA2 antibody, NPS-PLA2 antibody, PA2GA_HUMAN antibody, Phosphatidylcholine 2-acylhydrolase 2A antibody, Phosphatidylcholine 2acylhydrolase antibody, Phospholipase A2 antibody, Phospholipase A2 group IIA (platelets, synovial fluid) antibody, Phospholipase A2 membrane associated antibody, Phospholipase A2 polypeptide B antibody, Phospholipase A2 synovial antibody, PLA2 antibody, PLA2B antibody, PLA2G2A antibody, PLA2L antibody, PLA2S antibody, PLAS1 antibody, RASF A antibody, sPLA2 antibody

UniProt: P14555

Pathways: Stem Cell Maintenance, Inositol Metabolic Process