PPP2R4 anticorps (AA 1-250)

N° du produit ABIN7169262

Détail du produit anti-PPP2R4 anticorps

Antigène: PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))

Épitope: AA 1-250

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPP2R4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Serine/threonine-protein phosphatase 2A activator protein (1-250AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:1000-1:2000, IF:1:200-1:500,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PPP2R4

Antigène: PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))

Autre désignation: PTPA (PPP2R4 Produits)

Synonymes: anticorps PP2A, anticorps PR53, anticorps PTPA, anticorps 2610042B21Rik, anticorps C77440, anticorps N28142, anticorps PTPRA, anticorps Ppp2r4, anticorps fc23d07, anticorps ppp2r4, anticorps wu:fc23d07, anticorps zgc:92766, anticorps pp2a, anticorps ppp2r4.L, anticorps pr53, anticorps ptpa, anticorps protein phosphatase 2 phosphatase activator, anticorps protein phosphatase 2 protein activator, anticorps protein phosphatase 2 phosphatase activator L homeolog, anticorps PTPA, anticorps Ptpa, anticorps ptpa, anticorps ptpa.L

Sujet:

Background: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for serine/threonine-protein phosphatase 2A (PP2A) modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg(2+) (By similarity). Reversibly stimulates the variable phosphotyrosyl phosphatase activity of PP2A core heterodimer PP2A(D) in presence of ATP and Mg(2+) (in vitro). The phosphotyrosyl phosphatase activity is dependent of an ATPase activity of the PP2A(D):PPP2R4 complex. Is involved in apoptosis, the function appears to be independent from PP2A.

Aliases: subunit B'' antibody, KIAA0044 antibody, MGC2184 antibody, Phosphotyrosyl phosphatase activator antibody, PP2A antibody, PP2A phosphatase activator antibody, PP2A subunit B' antibody, PP2A subunit B' isoform PR53 antibody, PP2A subunit B' PR53 isoform antibody, PPP2R4 antibody, PR53 antibody, PR53 isoform antibody, Protein phosphatase 2, regulatory subunit B-prime antibody, Protein phosphatase 2A activator regulatory subunit 4 antibody, Protein phosphatase 2A regulatory subunit B' (PR 53) antibody, PTPA antibody, PTPA_HUMAN antibody, Serine/threonine protein phosphatase 2A regulatory subunit B' antibody, Serine/threonine-protein phosphatase 2A activator antibody, Serine/threonine-protein phosphatase 2A regulatory subunit 4 antibody, Serine/threonine-protein phosphatase 2A regulatory subunit B'' antibody

UniProt: Q15257

Pathways: Signalisation PI3K-Akt, M Phase, Hepatitis C, Toll-Like Receptors Cascades