STAT2 anticorps (AA 571-851)

N° du produit ABIN7169671

Détail du produit anti-STAT2 anticorps

Antigène: STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))

Épitope: AA 571-851

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STAT2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Signal transducer and activator of transcription 2 protein (571-851AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur STAT2

Antigène: STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))

Autre désignation: STAT2 (STAT2 Produits)

Synonymes: anticorps wu:fj84d07, anticorps p113, anticorps stat2, anticorps 1600010G07Rik, anticorps AW496480, anticorps ISGF-3, anticorps P113, anticorps STAT113, anticorps signal transducer and activator of transcription 2, anticorps AGAP000099-PA, anticorps stat2, anticorps STAT2, anticorps Stat2

Sujet:

Background: Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

Aliases: Homo sapiens interferon alpha induced transcriptional activator antibody, interferon alpha induced transcriptional activator antibody, ISGF 3 antibody, ISGF3 antibody, MGC59816 antibody, P113 antibody, signal transducer and activator of transcription 2 113kD antibody, Signal transducer and activator of transcription 2 antibody, STAT113 antibody, Stat2 antibody, STAT2_HUMAN antibody

UniProt: P52630

Pathways: Signalistation JAK/STAT, Hepatitis C, CXCR4-mediated Signaling Events