SART3 anticorps (AA 600-900)

N° du produit ABIN7170663

Détail du produit anti-SART3 anticorps

Antigène: SART3 (Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3))

Épitope: AA 600-900

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SART3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Squamous cell carcinoma antigen recognized by T-cells 3 protein (600-900AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SART3

Antigène: SART3 (Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3))

Autre désignation: SART3 (SART3 Produits)

Synonymes: anticorps SART3, anticorps DKFZp469J2418, anticorps si:ch211-191d15.4, anticorps wu:fc51h03, anticorps DSAP1, anticorps P100, anticorps RP11-13G14, anticorps TIP110, anticorps p110, anticorps p110(nrb), anticorps AU045857, anticorps mKIAA0156, anticorps squamous cell carcinoma antigen recognized by T-cells 3, anticorps squamous cell carcinoma antigen recognized by T-cells 3 L homeolog, anticorps squamous cell carcinoma antigen recognized by T cells 3, anticorps SART3, anticorps sart3, anticorps sart3.L, anticorps Sart3

Sujet:

Background: U6 snRNP-binding protein that functions as a recycling factor of the splicing machinery. Promotes the initial reassembly of U4 and U6 snRNPs following their ejection from the spliceosome during its maturation (PubMed:12032085). Also binds U6atac snRNPs and may function as a recycling factor for U4atac/U6atac spliceosomal snRNP, an initial step in the assembly of U12-type spliceosomal complex. The U12-type spliceosomal complex plays a role in the splicing of introns with non-canonical splice sites (PubMed:14749385). May also function as a substrate-targeting factor for deubiquitinases like USP4 and USP15. Recruits USP4 to ubiquitinated PRPF3 within the U4/U5/U6 tri-snRNP complex, promoting PRPF3 deubiquitination and thereby regulating the spliceosome U4/U5/U6 tri-snRNP spliceosomal complex disassembly (PubMed:20595234). May also recruit the deubiquitinase USP15 to histone H2B and mediate histone deubiquitination, thereby regulating gene expression and/or DNA repair (PubMed:24526689). May play a role in hematopoiesis probably through transcription regulation of specific genes including MYC (By similarity).

Aliases: DSAP1 antibody, hSART 3 antibody, hSART-3 antibody, P100 antibody, P110 antibody, p110(nrb) antibody, RP11 13G14 antibody, SART 3 antibody, SART-3 antibody, SART3 antibody, SART3_HUMAN antibody, Squamous cell carcinoma antigen recognized by T cells 3 antibody, Squamous cell carcinoma antigen recognized by T-cells 3 antibody, Tat interacting protein of 110 kDa antibody, Tat-interacting protein of 110 kDa antibody, Tip110 antibody

UniProt: Q15020

Pathways: Ribonucleoprotein Complex Subunit Organization