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SMARCE1 anticorps (AA 20-243)

SMARCE1 Reactivité: Humain IHC, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7171083
  • Antigène Voir toutes SMARCE1 Anticorps
    SMARCE1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily E, Member 1 (SMARCE1))
    Épitope
    • 15
    • 9
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 20-243
    Reactivité
    • 61
    • 28
    • 23
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Humain
    Hôte
    • 54
    • 6
    • 1
    Lapin
    Clonalité
    • 49
    • 12
    Polyclonal
    Conjugué
    • 33
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp SMARCE1 est non-conjugé
    Application
    • 42
    • 28
    • 23
    • 13
    • 10
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 protein (20-243AA)
    Isotype
    IgG
    Top Product
    Discover our top product SMARCE1 Anticorps primaire
  • Indications d'application
    Recommended dilution: IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    SMARCE1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily E, Member 1 (SMARCE1))
    Autre désignation
    SMARCE1 (SMARCE1 Produits)
    Synonymes
    anticorps BAF57, anticorps XBaf57, anticorps MGC52696, anticorps MGC69429, anticorps MGC81726, anticorps SMARCE1, anticorps DKFZp459O2235, anticorps fb54d11, anticorps wu:fb33d02, anticorps wu:fb54d11, anticorps Baf57, anticorps 2810417B20Rik, anticorps 5830412H02Rik, anticorps 9030408N19Rik, anticorps Baf27, anticorps RGD1304726, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 L homeolog, anticorps smarce1, anticorps SMARCE1, anticorps smarce1.L, anticorps Smarce1
    Sujet

    Background: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). Required for the coactivation of estrogen responsive promoters by Swi/Snf complexes and the SRC/p160 family of histone acetyltransferases (HATs). Also specifically interacts with the CoREST corepressor resulting in repression of neuronal specific gene promoters in non-neuronal cells.

    Aliases: BAF57 antibody, BRG1 associated factor 57 antibody, BRG1-associated factor 57 antibody, Chromatin remodeling complex BRG1 associated factor 57 antibody, FLJ35648 antibody, SMARCE 1 antibody, SMARCE1 antibody, SMCE1_HUMAN antibody, SWI/SNF related matrix associated actin dependent regulator of chromatin e1 antibody, SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily e member 1 antibody, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 antibody

    UniProt
    Q969G3
    Pathways
    Chromatin Binding
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