GTPase NRas anticorps
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- Antigène Voir toutes GTPase NRas (NRAS) Anticorps
- GTPase NRas (NRAS)
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GTPase NRas est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Antigen affinity purification
- Immunogène
- Synthetic peptide of Human NRAS
- Isotype
- IgG
- Top Product
- Discover our top product NRAS Anticorps primaire
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- Indications d'application
- ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- GTPase NRas (NRAS)
- Autre désignation
- NRAS (NRAS Produits)
- Synonymes
- anticorps NRAS, anticorps AV095280, anticorps N-ras, anticorps ALPS4, anticorps NRAS1, anticorps NS6, anticorps N-RAS, anticorps fj99a10, anticorps wu:fj99a10, anticorps zgc:100761, anticorps zras-b1, anticorps H-RAS, anticorps HRAS, anticorps GTPase NRas, anticorps neuroblastoma RAS viral (v-ras) oncogene homolog L homeolog, anticorps NRAS proto-oncogene, GTPase, anticorps neuroblastoma ras oncogene, anticorps neuroblastoma RAS viral oncogene homolog, anticorps Tsp_01117, anticorps nras.L, anticorps Nras, anticorps NRAS, anticorps nras
- Sujet
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Background: This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
Aliases: ALPS4 antibody, AV095280 antibody, GTPase NRas antibody, HRAS1 antibody, N ras antibody, N ras protein part 4 antibody, Neuroblastoma RAS viral (v ras) oncogene homolog antibody, NRAS antibody, NRAS1 antibody, NS6 antibody, OTTHUMP00000013879 antibody, OTTMUSP00000023521 antibody, RASN_HUMAN antibody, Transforming protein N Ras antibody, Transforming protein N-Ras antibody, v ras neuroblastoma RAS viral oncogene homolog antibody
- UniProt
- P01111
- Pathways
- Signalisation p53, Signalisation MAPK, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
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