C1r LC (AA 420-500), (Cleaved-Ile464) anticorps

N° du produit ABIN7212430

Cet anticorps Lapin Polyclonal détecte spécifiquement C1r LC dans ELISA et WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour C1r LC (AA 420-500), (Cleaved-Ile464) anticorps (ABIN7212430)

Antigène: C1r LC

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: ELISA, Western Blotting (WB)

Détail du produit

Épitope: AA 420-500, Cleaved-Ile464

Fonction: Rabbit Anti-Cleaved-C1r LC (I464) Polyclonal Antibody

Specificité: Cleaved-C1r LC (I464) Polyclonal Antibody detects endogenous levels of fragment of activated C1r LC protein resulting from cleavage adjacent to I464.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human C1r LC at AA range: 420-500

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détail du antigène

Antigène: C1r LC

Sujet: C1R, Complement C1r subcomponent, Complement component 1 subcomponent rC1R (Complement C1r Subcomponent) is a Protein Coding gene. Diseases associated with C1R include immunodeficiency due to an early component of complement deficiency and c1r/c1s deficiency, combined. Among its related pathways are Complement and coagulation cascades and Immune System. GO annotations related to C1R include calcium ion binding and serine-type peptidase activity. An important paralog of C1R is HP.C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.C1R aligns across a gap in the GRCh38 reference genome assembly, and therefore, the 5' end of C1R was annotated on NT_009714.18 and the 3' end was annotated on NT_009759.17 in NCBI's Homo sapiens Annotation Release 106.

Poids moléculaire: 27kD

ID gène: 715

UniProt: P00736