IFNA anticorps (AA 101-189)

N° du produit ABIN717131

Détail du produit anti-IFNA anticorps

Antigène: IFNA (Interferon alpha (IFNA))

Épitope: AA 101-189

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFNA est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody will detect Human IFN-Alpha subtypes 2,4,5,6,7,8,10,14,16,17 and has lower affinity for IFNA1/13. This antibody will detect Mouse IFN-Alpha subtypes 1,2,5,7,12,13,14,16

Réactivité croisée: Souris

Homologie: Human

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human IFNA4

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur IFNA

Antigène: IFNA (Interferon alpha (IFNA))

Autre désignation: IFN-Alpha (IFNA Produits)

Synonymes: anticorps IFN-alphaO, anticorps IFN-ALPHA-1, anticorps IFN1@, anticorps Ifa, anticorps Ifa8, anticorps interferon alpha 16, anticorps interferon, alpha 1, anticorps interferon alpha, anticorps interferon-alpha, anticorps IFNA16, anticorps IFNA1, anticorps Ifna, anticorps IFNA

Sujet:

Synonyms: IFNA, IFN-a, IFN-_, Interferon alpha, Interferon-alpha, IFNA2, IFNA4, IFNA6, IFNA7, IFNA8, IFNA10, IFNA16, IFNA17, IFNA5, IFNA21, IFNA14, IFNA1, IFNA13, Pan Interferon alpha

Background: Interferon-_ (IFN-_, also known as IFN-alpha, IFN-a, IFNA and Interferon-alpha) is a type I interferon and exists as 13 subtypes: IFN-_ 1, 2, 4, 5, 6, 7, 8, 10, 13, 14, 16, 17 and 21. They are mainly produced by virus-infected cells after sensing the presence of danger signals such as viral DNA or RNA. The binding of IFN-_ to its receptor initiates an anti-viral response, but also anti-tumor effects have been shown. A key producer of type I interferons is the plasmacytoid dendritic cell.

ID gène: 3441

UniProt: P05014

Pathways: Signalistation JAK/STAT, Signalisation TLR, Hepatitis C, Inflammasome