NFATC2IP anticorps (AA 290-360)

N° du produit ABIN7268978

Détail du produit anti-NFATC2IP anticorps

Antigène: NFATC2IP (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 Interacting Protein (NFATC2IP))

Épitope: AA 290-360

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFATC2IP est non-conjugé

Application: Western Blotting (WB)

Fonction: NFATC2IP Rabbit pAb

Séquence: VDHMATHLGV SPSRILLLFG ETELSPTATP RTLKLGVADI IDCVVLTSSP EATETSQQLQ LRVQGKEKHQ T

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 290-360 of human NFATC2IP (NP_116204.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NFATC2IP

Antigène: NFATC2IP (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 Interacting Protein (NFATC2IP))

Autre désignation: NFATC2IP (NFATC2IP Produits)

Synonymes: anticorps wu:fj84d09, anticorps NFATC2IP, anticorps D7Ertd304e, anticorps NIP45, anticorps ESC2, anticorps RAD60, anticorps nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein, anticorps nuclear factor of activated T-cells 2 interacting protein, anticorps nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein, anticorps nfatc2ip, anticorps NFATC2IP, anticorps Nfatc2ip

Sujet: In T-helper 2 (Th2 cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter, this leads to enhancement of histone H4 'Arg-3'-methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression (By similarity. Down-regulates formation of poly-SUMO chains by UBE2I/UBC9 (By similarity.,NFATC2IP,ESC2,NIP45,RAD60,Epigenetics & Nuclear Signaling,Signal Transduction,Immunology & Inflammation,Cytokines,Cell Intrinsic Innate Immunity Signaling Pathway,NFATC2IP

Poids moléculaire: 13kDa/15kDa/45kDa

ID gène: 84901

UniProt: Q8NCF5