RAPGEF3 anticorps

N° du produit ABIN7269850

Détail du produit anti-RAPGEF3 anticorps

Antigène: RAPGEF3 (Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp RAPGEF3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Fonction: Epac1/RAPGEF3 Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human Epac1/RAPGEF3

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RAPGEF3

Antigène: RAPGEF3 (Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3))

Autre désignation: RAPGEF3 (RAPGEF3 Produits)

Synonymes: anticorps RAPGEF3, anticorps epac, anticorps si:dkey-27m20.2, anticorps CAMP-GEFI, anticorps EPAC, anticorps EPAC1, anticorps HSU79275, anticorps bcm910, anticorps 2310016P22Rik, anticorps 9330170P05Rik, anticorps Epac, anticorps Epac1, anticorps Rap guanine nucleotide exchange factor 3, anticorps Rap guanine nucleotide exchange factor 3 S homeolog, anticorps Rap guanine nucleotide exchange factor (GEF) 3, anticorps RAPGEF3, anticorps rapgef3.S, anticorps rapgef3, anticorps Rapgef3

Sujet: Guanine nucleotide exchange factor (GEF for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which it activates the PI3K gamma complex and which is involved in angiogenesis. Plays a role in the modulation of the cAMP-induced dynamic control of endothelial barrier function through a pathway that is independent on Rho-mediated signaling. Required for the actin rearrangement at cell-cell junctions, such as stress fibers and junctional actin.,CAMP-GEFI, EPAC, EPAC1, HSU79275, bcm910,Endocrine & Metabolism,G protein signaling,G protein signaling_G-Protein-Coupled Receptors Signaling to MAPK/Erk,Immunology & Inflammation,MAPK-Erk Signaling Pathway,Signal Transduction,RAPGEF3

Poids moléculaire: 104kDa

ID gène: 10411

UniProt: O95398

Pathways: cAMP Metabolic Process