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SMAD2 anticorps

KO Validated SMAD2 Reactivité: Humain WB, IF, IP Hôte: Lapin Monoclonal unconjugated
N° du produit ABIN7270344
  • Antigène Voir toutes SMAD2 Anticorps
    SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))
    Reactivité
    • 237
    • 152
    • 119
    • 12
    • 12
    • 9
    • 9
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    Humain
    Hôte
    • 238
    • 12
    Lapin
    Clonalité
    • 213
    • 37
    Monoclonal
    Conjugué
    • 128
    • 18
    • 12
    • 10
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    Cet anticorp SMAD2 est non-conjugé
    Application
    • 212
    • 101
    • 64
    • 53
    • 52
    • 45
    • 41
    • 41
    • 18
    • 14
    • 11
    • 10
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
    Fonction
    [KO Validated] Smad2 Rabbit mAb
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Monoclonal Antibodies
    Purification
    Affinity purification
    Classe de qualité
    KO Validated
    Immunogène
    A synthesized peptide derived from human Smad2
    Isotype
    IgG
    Top Product
    Discover our top product SMAD2 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))
    Autre désignation
    SMAD2 (SMAD2 Produits)
    Synonymes
    anticorps JV18, anticorps JV18-1, anticorps MADH2, anticorps MADR2, anticorps hMAD-2, anticorps hSMAD2, anticorps jv18, anticorps Xmad2, anticorps madh2, anticorps madr2, anticorps XSmad2, anticorps hmad-2, anticorps hsmad2, anticorps jv18-1, anticorps smad-2, anticorps fj43c06, anticorps wu:fj43c06, anticorps 7120426M23Rik, anticorps Madh2, anticorps Madr2, anticorps Smad-2, anticorps mMad2, anticorps MAD homolog 2, anticorps Mothers against DPP homolog 2, anticorps SMAD 2, anticorps Smad2, anticorps SMAD family member 2, anticorps SMAD family member 2-Z, anticorps SMAD family member 2 S homeolog, anticorps SMAD2, anticorps SMAD2Z, anticorps smad2, anticorps smad2.S, anticorps Smad2
    Sujet
    The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012],JV18;JV18-1;MADH2;MADR2;hMAD-2;hSMAD2;Smad2;SMAD2,Angiogenesis,Cancer,Cardiovascular,Cell Biology & Developmental Biology,Epigenetics & Nuclear Signaling,ESC Pluripotency and Differentiation,Growth factors,Protein phosphorylation,Signal Transduction,Stem Cells,TGF-b-Smad Signaling Pathway,TGF-b-Smad Signaling Pathway_SMADs,Transcription Factors,SMAD2
    Poids moléculaire
    58kDa
    ID gène
    4087
    UniProt
    Q15796
    Pathways
    Cycle Cellulaire, Hormone Transport, Chromatin Binding, Protein targeting to Nucleus
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