MAFK anticorps
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- Antigène Voir toutes MAFK Anticorps
- MAFK (Transcription Factor MafK (MAFK))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MAFK est non-conjugé
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Application
- Western Blotting (WB)
- Fonction
- MAFK Rabbit pAb
- Réactivité croisée
- Humain
- Attributs du produit
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogène
- A synthetic peptide of Human MAFK.
- Isotype
- IgG
- Top Product
- Discover our top product MAFK Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- MAFK (Transcription Factor MafK (MAFK))
- Autre désignation
- MAFK (MAFK Produits)
- Synonymes
- anticorps NFE2U, anticorps P18, anticorps AW061068, anticorps NF-E2, anticorps Nfe2u, anticorps MAF bZIP transcription factor K, anticorps v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian), anticorps v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K, anticorps Mafk, anticorps MAFK, anticorps mafk
- Sujet
- The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD, MIM 609806) and ferrochelatase (FECH, MIM 612386). NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG (MIM 602020), or MafK) and p45 (MIM 601490). Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160). Maf homodimers suppress transcription at NFE2 sites.[supplied by OMIM, Nov 2008],NFE2U,P18,MAFK,Epigenetics & Nuclear Signaling,Transcription Factors,MAFK
- ID gène
- 7975
- UniProt
- O60675
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