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DR3/LARD anticorps (AA 240-426)

TNFRSF25 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7271071
  • Antigène Voir toutes DR3/LARD (TNFRSF25) Anticorps
    DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))
    Épitope
    • 15
    • 15
    • 8
    • 7
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 240-426
    Reactivité
    • 83
    • 29
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 73
    • 12
    • 1
    Lapin
    Clonalité
    • 72
    • 13
    Polyclonal
    Conjugué
    • 39
    • 7
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp DR3/LARD est non-conjugé
    Application
    • 72
    • 35
    • 26
    • 26
    • 9
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Fonction
    TNFRSF25 Rabbit pAb
    Séquence
    KPLVTADEAG MEALTPPPAT HLSPLDSAHT LLAPPDSSEK ICTVQLVGNS WTPGYPETQE ALCPQVTWSW DQLPSRALGP AAAPTLSPES PAGSPAMMLQ PGPQLYDVMD AVPARRWKEF VRTLGLREAE IEAVEVEIGR FRDQQYEMLK RWRQQQPAGL GAVYAALERM GLDGCVEDLR SRLQRGP
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 240-426 of human TNFRSF25 (NP_683866.1).
    Isotype
    IgG
    Top Product
    Discover our top product TNFRSF25 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))
    Autre désignation
    TNFRSF25 (TNFRSF25 Produits)
    Synonymes
    anticorps APO-3, anticorps DDR3, anticorps DR3, anticorps LARD, anticorps TNFRSF12, anticorps TR3, anticorps TRAMP, anticorps WSL-1, anticorps WSL-LR, anticorps Tnfrsf12, anticorps Wsl, anticorps TNFRSF25, anticorps TNF receptor superfamily member 25, anticorps tumor necrosis factor receptor superfamily, member 25, anticorps TNFRSF25, anticorps Tnfrsf25
    Sujet
    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation.,TNFRSF25,APO-3,DDR3,DR3,LARD,TNFRSF12,TR3,TRAMP,WSL-1,WSL-LR,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Death Receptor Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,TNFRSF25
    Poids moléculaire
    13-29kDa/40-45kDa
    ID gène
    8718
    UniProt
    Q93038
    Pathways
    Apoptose
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