CD2AP anticorps (AA 689-639)

N° du produit ABIN7450093

Cet anticorps Lapin Polyclonal détecte spécifiquement CD2AP dans WB et IP. Il présente une réactivité envers Humain.

Aperçu rapide pour CD2AP anticorps (AA 689-639) (ABIN7450093)

Antigène: CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD2AP est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-CD2AP anticorps

Épitope: AA 689-639

Fonction: Rabbit anti-CD2AP Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 689 and 639

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur CD2AP

Antigène: CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

Autre désignation: CD2AP

Sujet: Background: CD2-associated protein (CD2AP) seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, it modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. It also controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. CD2AP may play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell and may anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. CD2AP is also required for cytokinesis [taken from the Universal Protein Resource (UniProt) Q9Y5K6].

ID gène: 23607

NCBI Accession: NP_036252

UniProt: Q9Y5K6