KCNN4 anticorps (AA 325-427)

N° du produit ABIN719786

Détail du produit anti-KCNN4 anticorps

Antigène: KCNN4 (Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4))

Épitope: AA 325-427

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNN4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Rat

Homologie: Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human KCNN4

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-KCNN4 (ABIN719786)

Lively, Lam, Wong, Schlichter: "Comparing Effects of Transforming Growth Factor β1 on Microglia From Rat and Mouse: Transcriptional Profiles and Potassium Channels." dans: Frontiers in cellular neuroscience, Vol. 12, pp. 115, (2018) (PubMed).

Zhang, Yang, Yin, Yi, Shen, Zhao, Zhu, Liu: "Inhibition of SK4 Potassium Channels Suppresses Cell Proliferation, Migration and the Epithelial-Mesenchymal Transition in Triple-Negative Breast Cancer Cells." dans: PLoS ONE, Vol. 11, Issue 4, pp. e0154471, (2016) (PubMed).

Détails sur KCNN4

Antigène: KCNN4 (Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4))

Autre désignation: KCNN4 (KCNN4 Produits)

Synonymes: anticorps KCa3.1, anticorps IK1, anticorps IKCA1, anticorps KCA4, anticorps SK4, anticorps hIKCa1, anticorps hKCa4, anticorps hSK4, anticorps rKCNN4c, anticorps rSK4, anticorps SKCas, anticorps mIKCa1, anticorps potassium calcium-activated channel subfamily N member 4, anticorps potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4, anticorps KCNN4, anticorps Kcnn4

Sujet:

Synonyms: IK1, SK4, KCA4, hSK4, IKCA1, hKCa4, KCa3.1, hIKCa1, Intermediate conductance calcium-activated potassium channel protein 4, SKCa 4, SKCa4, Putative Gardos channel, KCNN4

Background: Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin.

ID gène: 3783

UniProt: O15554