CYP17A1 anticorps (AA 24-65)

N° du produit ABIN720071

Détail du produit anti-CYP17A1 anticorps

Antigène: CYP17A1 (Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1))

Épitope: AA 24-65

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP17A1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Souris, Rat

Homologie: Human,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Cytochrome P450 17A1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-CYP17A1 (ABIN720071)

Han, Xie, Zhang, Zhang, Zhang, Han, Yuan, Weng: "Seasonal expression of P450c17 and 5α-reductase-2 in the scented gland of male muskrats (Ondatra zibethicus)." dans: General and comparative endocrinology, Vol. 254, pp. 60-67, (2018) (PubMed).

Zhang, Zhao, Zhang, Hao, Yu, Min, Li, Ma, Chen, Yi, Tang, Meng, Liu, Wang, Shen, Zhang: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." dans: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).

Wilsher, Stansfield, Greenwood, Trethowan, Anderson, Wooding, Allen: "Ovarian and placental morphology and endocrine functions in the pregnant giraffe (Giraffa camelopardalis)." dans: Reproduction (Cambridge, England), Vol. 145, Issue 6, pp. 541-54, (2013) (PubMed).

Détails sur CYP17A1

Antigène: CYP17A1 (Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1))

Autre désignation: Cytochrome P450 17a1 (CYP17A1 Produits)

Synonymes: anticorps cyp17, anticorps CYPXVII, anticorps P450c17, anticorps cyp17a1, anticorps P450-C17, anticorps wu:fi13g04, anticorps wu:fi17b11, anticorps wu:fi31c08, anticorps zgc:136516, anticorps zgc:66494, anticorps P45017A1, anticorps CYP17, anticorps CPT7, anticorps P450C17, anticorps S17AH, anticorps Cyp17, anticorps p450c17, anticorps cytochrome P450 17A1, anticorps cytochrome P450, family 17, subfamily A, polypeptide 1, anticorps steroidogenic cytochrome P450 17-hydroxylase/lyase, anticorps cytochrome P450 family 17 subfamily A member 1 L homeolog, anticorps cytochrome P450 family 17 subfamily A member 1, anticorps cytochrome P-450 17 alpha-hydroxylase/C17,20-lyase, anticorps cytochrome P450, family 17, subfamily a, polypeptide 1, anticorps cytochrome P450c17, anticorps CpipJ_CPIJ010537, anticorps CpipJ_CPIJ010543, anticorps PTRG_02047, anticorps cyp17a1, anticorps cyp17, anticorps cyp17a1.L, anticorps CYP17A1, anticorps Cyp17a1

Sujet:

Synonyms: CPT7, CYP17, S17AH, P450C17, Steroid 17-alpha-hydroxylase/17,20 lyase, 17-alpha-hydroxyprogesterone aldolase, CYPXVII, Cytochrome P450 17A1, Cytochrome P450-C17, Cytochrome P450c17, Steroid 17-alpha-monooxygenase, CYP17A1

Background: Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty.

ID gène: 1586

UniProt: P05093

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin