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Cytochrome C anticorps (AA 51-105)

CYCS Reactivité: Humain, Rat, Souris, Lapin, Poulet WB, ELISA, FACS, IHC (p), ICC, IF (p), IHC (fro), IF (cc) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN723590
  • Antigène Voir toutes Cytochrome C (CYCS) Anticorps
    Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
    Épitope
    • 15
    • 13
    • 10
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-105
    Reactivité
    • 146
    • 116
    • 96
    • 44
    • 32
    • 24
    • 22
    • 18
    • 18
    • 16
    • 7
    • 7
    • 6
    • 6
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris, Lapin, Poulet
    Hôte
    • 85
    • 76
    • 7
    • 1
    Lapin
    Clonalité
    • 89
    • 79
    • 1
    Polyclonal
    Conjugué
    • 105
    • 13
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Cytochrome C est non-conjugé
    Application
    • 136
    • 50
    • 43
    • 38
    • 36
    • 32
    • 26
    • 25
    • 13
    • 13
    • 13
    • 12
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc))
     Réactivité croisée
    Poulet, Humain, Souris, Lapin, Rat
    Homologie
    Cow,Pig,Horse,Guinea Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Cytochrome C
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Liu, Chen, Du, Wu, Dong, Qu, Fan, Yao: "GluR3B Ab's induced oligodendrocyte precursor cells excitotoxicity via mitochondrial dysfunction." dans: Brain research bulletin, Vol. 130, pp. 60-66, (2017) (PubMed).

    Abdel-Hamid, El-Azab, Moustafa: "Macrolide antibiotics differentially influence human HepG2 cytotoxicity and modulate intrinsic/extrinsic apoptotic pathways in rat hepatocellular carcinoma model." dans: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 390, Issue 4, pp. 379-395, (2017) (PubMed).

    Tian, Wang, Zhang, Luo, Jiang, Zhang, Mei, Wu, Wu, Peng, Long, Luo, Guo: "Phosphoprotein Gene Contributes to the Enhanced Apoptosis Induced by Wild-Type Rabies Virus GD-SH-01 In Vitro." dans: Frontiers in microbiology, Vol. 8, pp. 1697, (2017) (PubMed).

    Gu, Chen, Jiang, Zhang: "ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction underlie apoptosis induced by resveratrol and arsenic trioxide in A549 cells." dans: Chemico-biological interactions, Vol. 245, pp. 100-9, (2016) (PubMed).

    Duan, Li, Li, Xing, Zhang, Li, Zhao, Sun, Gao, Li et al.: "Antioxidant tert-butylhydroquinone ameliorates arsenic-induced intracellular damages and apoptosis through induction of Nrf2-dependent antioxidant responses as well as stabilization of anti-apoptotic ..." dans: Free radical biology & medicine, Vol. 94, pp. 74-87, (2016) (PubMed).

    Zhang, He, Guo, Li, Wang, Yang, Cui: "Sulfiredoxin-1 protects against simulated ischaemia/reperfusion injury in cardiomyocyte by inhibiting PI3K/AKT-regulated mitochondrial apoptotic pathways." dans: Bioscience reports, Vol. 36, Issue 2, (2016) (PubMed).

    Gu, Chen, Jiang, Zhang: "Resveratrol Synergistically Triggers Apoptotic Cell Death with Arsenic Trioxide via Oxidative Stress in Human Lung Adenocarcinoma A549 Cells." dans: Biological trace element research, Vol. 163, Issue 1-2, pp. 112-23, (2015) (PubMed).

    Gao, Yu, Yan, Li, Shen, Jia, Guan, Gao, Kan: "Poly (ADP?ribose) polymerase? and cytochrome c?mediated apoptosis induces hepatocyte injury in a rat model of hyperammonia?induced hepatic failure." dans: Molecular medicine reports, (2015) (PubMed).

    Li, Li, Sun, Ni, Chen, Guo, Chen: "Increased Expression of Mitochondrial Inner-Membrane Protein Mpv17 After Intracerebral Hemorrhage in Adult Rats." dans: Neurochemical research, Vol. 40, Issue 8, pp. 1620-30, (2015) (PubMed).

    Chen, Gu, Jiang, Zhang: "Nuclear translocation of nuclear factor kappa B is regulated by G protein signaling pathway in arsenite-induced apoptosis in HBE cell line." dans: Environmental toxicology, (2015) (PubMed).

    Ye, Wu, Li, Li, Zheng, Liu, Ye: "Millimeter Wave Treatment Inhibits Apoptosis of Chondrocytes via Regulation Dynamic Equilibrium of Intracellular Free Ca (2+)." dans: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 464161, (2015) (PubMed).

    Zhang, Ma, Qi, Wei, Zhang, Li, Chiu: "P62 regulates resveratrol-mediated Fas/Cav-1 complex formation and transition from autophagy to apoptosis." dans: Oncotarget, Vol. 6, Issue 2, pp. 789-801, (2015) (PubMed).

    Jiang, Ren, Jiang, Wang, Zhang, Yin, Wang, Qi, Wang, Feng: "Guanabenz delays the onset of disease symptoms, extends lifespan, improves motor performance and attenuates motor neuron loss in the SOD1 G93A mouse model of amyotrophic lateral sclerosis." dans: Neuroscience, Vol. 277, pp. 132-8, (2014) (PubMed).

    Chen, Jiang, Lai, Liu, Zhang: "Resveratrol protects against arsenic trioxide-induced oxidative damage through maintenance of glutathione homeostasis and inhibition of apoptotic progression." dans: Environmental and molecular mutagenesis, (2014) (PubMed).

    Fang, Zhang, Qi, Fan, Luo, Liu, Tan: "Evodiamine induces G2/M arrest and apoptosis via mitochondrial and endoplasmic reticulum pathways in H446 and H1688 human small-cell lung cancer cells." dans: PLoS ONE, Vol. 9, Issue 12, pp. e115204, (2014) (PubMed).

    Liao, Li, Li, Liu: "Organellar proteome analyses of ricin toxin-treated HeLa cells." dans: Toxicology and industrial health, (2014) (PubMed).

    Wang, Wang, Shan, Song, Dai, Wang, Chi: "Mu-calpain mediates hippocampal neuron death in rats after lithium-pilocarpine-induced status epilepticus." dans: Brain research bulletin, Vol. 76, Issue 1-2, pp. 90-6, (2008) (PubMed).

  • Antigène
    Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
    Autre désignation
    Cytochrome C (CYCS Produits)
    Synonymes
    anticorps CYC, anticorps HCS, anticorps THC4, anticorps cyct, anticorps cyc, anticorps hcs, anticorps CYCS, anticorps cytc, anticorps CYCSA, anticorps CG17903, anticorps Cyt C, anticorps Cyt c, anticorps Cyt-c2, anticorps CytC-2, anticorps Cytc, anticorps Cytc-p, anticorps DC4, anticorps DMc01, anticorps Dmel\\CG17903, anticorps cyt c, anticorps cyt c-p, anticorps cyt-c-p, anticorps cyt-c2, anticorps cyt.c, anticorps cytochrome c, anticorps dc4, anticorps pDMc01, anticorps wu:fk52b01, anticorps zgc:86706, anticorps ENSMUSG00000058927, anticorps cytochrome c, somatic, anticorps cytochrome c, somatic S homeolog, anticorps Cytochrome c proximal, anticorps cytochrome c, somatic b, anticorps cytochrome c, somatic pseudogene, anticorps cytochrome c-like, anticorps cytochrome c, anticorps CYCS, anticorps cycs.S, anticorps cycs, anticorps Cycs, anticorps Cyt-c-p, anticorps cycsb, anticorps Gm10053, anticorps LOC100724240, anticorps CYC, anticorps LOC100847700, anticorps LOC101107954, anticorps LOC106829744, anticorps LOC106992390, anticorps LOC102085712
    Sujet

    Synonyms: CYC, HCS, THC4, Cytochrome c, CYCS

    Background: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

    ID gène
    54205
    UniProt
    P99999
    Pathways
    Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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