HSP90AB1 anticorps (AA 635-724)

N° du produit ABIN725495

Détail du produit anti-HSP90AB1 anticorps

Antigène: HSP90AB1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class B Member 1 (HSP90AB1))

Épitope: AA 635-724

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSP90AB1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Pig,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HSP90 beta

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-HSP90AB1 (ABIN725495)

Bozok Cetintas, Acikgoz, Yigitturk, Demir, Oktem, Tezcanli Kaymaz, Oltulu, Aktug: "Effects of flavopiridol on critical regulation pathways of CD133high/CD44high lung cancer stem cells." dans: Medicine, Vol. 95, Issue 43, pp. e5150, (2016) (PubMed).

Mori, Akita, Tanida, Ishida, Toda, Inoue, Yashiro, Sawada, Hirakawa, Nakada et al.: "MUC1 protein induces urokinase-type plasminogen activator (uPA) by forming a complex with NF-κB p65 transcription factor and binding to the uPA promoter, leading to enhanced invasiveness of cancer ..." dans: The Journal of biological chemistry, Vol. 289, Issue 51, pp. 35193-204, (2015) (PubMed).

Ding, Wu, Su, Zhou, Zhao, Deng, Zhang, Liu, Wang, Liu: "Expression of heat shock protein 90 genes during early development and infection in Megalobrama amblycephala and evidence for adaptive evolution in teleost." dans: Developmental and comparative immunology, Vol. 41, Issue 4, pp. 683-93, (2013) (PubMed).

Détails sur HSP90AB1

Antigène: HSP90AB1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class B Member 1 (HSP90AB1))

Autre désignation: HSP90 beta (HSP90AB1 Produits)

Synonymes: anticorps D6S182, anticorps HSP84, anticorps HSP90B, anticorps HSPC2, anticorps HSPCB, anticorps GRP94, anticorps TRA1, anticorps hsp90b, anticorps 90kDa, anticorps AL022974, anticorps C81438, anticorps Hsp84, anticorps Hsp84-1, anticorps Hsp90, anticorps Hspcb, anticorps Hsp70, anticorps Hsp70-1, anticorps Hsp70.1, anticorps hsp68, anticorps HSP90-BETA, anticorps hsp90beta, anticorps wu:fa29f01, anticorps wu:fa91e11, anticorps wu:fd59e11, anticorps wu:gcd22h07, anticorps HSP90, anticorps heat shock protein 90 alpha family class B member 1, anticorps heat shock protein 90 beta family member 1, anticorps Heat Shock Protein 90, endoplasmic reticulum, anticorps heat shock protein 90B, anticorps heat shock protein 90 alpha (cytosolic), class B member 1, anticorps heat shock protein 1B, anticorps heat shock protein 90kDa alpha family class B member 1 S homeolog, anticorps heat shock protein 90, alpha (cytosolic), class B member 1, anticorps HSP90AB1, anticorps HSP90B1, anticorps HSP90B, anticorps hsp90ab1, anticorps Hsp90ab1, anticorps Hspa1b, anticorps hsp90ab1.S

Sujet:

Synonyms: HSP84, HSPC2, HSPCB, D6S182, HSP9B, Heat shock protein HSP 9-beta, HSP 9, Heat shock 84 kDa, HSP 84, HSP9AB1

Background: Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.

ID gène: 3326

UniProt: P08238

Pathways: Regulation of Cell Size