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BACE1 anticorps (AA 401-501)

BACE1 Reactivité: Humain, Souris, Rat WB, ELISA, IHC (p), ICC, FACS, IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN725705
  • Antigène Voir toutes BACE1 Anticorps
    BACE1 (Beta-secretase 1 (BACE1))
    Épitope
    • 15
    • 13
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 401-501
    Reactivité
    • 82
    • 51
    • 40
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 76
    • 11
    Lapin
    Clonalité
    • 71
    • 16
    Polyclonal
    Conjugué
    • 56
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BACE1 est non-conjugé
    Application
    • 64
    • 36
    • 29
    • 17
    • 13
    • 12
    • 12
    • 11
    • 11
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain, Souris, Rat
    Homologie
    Dog,Pig,Chicken,Rabbit,Guinea Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human BACE1
    Isotype
    IgG
    Top Product
    Discover our top product BACE1 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Ku, Li, Gao, Zhang, Yan, Ji, Li, Sang: "NF-κB-regulated microRNA-574-5p underlies synaptic and cognitive impairment in response to atmospheric PM2.5 aspiration." dans: Particle and fibre toxicology, Vol. 14, Issue 1, pp. 34, (2018) (PubMed).

    Hong, Shen, Yin, Sun, Ma, Liu: "Effects of RAGE-Specific Inhibitor FPS-ZM1 on Amyloid-β Metabolism and AGEs-Induced Inflammation and Oxidative Stress in Rat Hippocampus." dans: Neurochemical research, Vol. 41, Issue 5, pp. 1192-9, (2016) (PubMed).

    Yan, Yun, Ku, Li, Sang: "NO2 inhalation promotes Alzheimer's disease-like progression: cyclooxygenase-2-derived prostaglandin E2 modulation and monoacylglycerol lipase inhibition-targeted medication." dans: Scientific reports, Vol. 6, pp. 22429, (2016) (PubMed).

    Jiao, Kong, Yao, Li, Tao, Yan, Yang: "Osthole decreases beta amyloid levels through up-regulation of miR-107 in Alzheimer's disease." dans: Neuropharmacology, Vol. 108, pp. 332-44, (2016) (PubMed).

    Tian, Guo, Wu, Ma, Zhao: "Minocycline Alleviates Sevoflurane-Induced Cognitive Impairment in Aged Rats." dans: Cellular and molecular neurobiology, (2015) (PubMed).

  • Antigène
    BACE1 (Beta-secretase 1 (BACE1))
    Autre désignation
    BACE1 (BACE1 Produits)
    Synonymes
    anticorps ASP2, anticorps BACE, anticorps HSPC104, anticorps C76936, anticorps Bace, anticorps MGC145931, anticorps BACE1, anticorps zgc:77409, anticorps beta-secretase 1, anticorps beta-site APP cleaving enzyme 1, anticorps beta-site APP-cleaving enzyme 1, anticorps BACE1, anticorps Bace1, anticorps bace1
    Sujet

    Synonyms: ASP2, BACE, HSPC104, Beta-secretase 1, Aspartyl protease 2, Asp 2, Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, Memapsin-2, Membrane-associated aspartic protease 2, BACE1, KIAA1149

    Background: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.

    ID gène
    23621
    UniProt
    P56817
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