IL1B anticorps (Interleukin 1, beta) (AA 120-170)

Details for Product anti-IL1B Antibody No. ABIN728503
Antigène
  • il1-b
  • zgc:111873
  • IL-1beta
  • Il-1b
  • IL1B
  • IL-1
  • IL1-BETA
  • IL1F2
  • IL-1BETA
  • IL1beta
  • IL-1B
  • interleukin 1, beta
  • interleukin 1 beta
  • il1b
  • Il1b
  • IL1B
Épitope
AA 120-170
27
24
16
15
15
15
13
12
11
10
8
8
7
6
6
5
5
5
5
4
4
4
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivité
Chien, Humain, Souris, Lapin, Rat (Rattus)
351
166
120
37
22
21
16
14
12
11
9
9
8
4
4
2
2
1
Hôte
Lapin
421
174
15
8
8
8
2
2
Clonalité
Polyclonal
Conjugué
Cet anticorp IL1B est non-conjugé
84
35
23
12
6
4
4
4
3
3
3
3
3
3
3
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
444
340
194
67
65
56
43
36
33
31
30
23
22
16
13
5
4
4
3
3
3
3
2
2
2
1
1
1
1
Options
Immunogène KLH conjugated synthetic peptide derived from human IL-1beta
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others IL1B products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation IL-1 beta (IL1B Antibody Extrait)
Sujet

Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.

Subcellular location: Secreted

Synonyms: IL-1, IL1F2, IL1-BETA, Interleukin-1 beta, IL-1 beta, Catabolin, IL1B

ID gène 3553
UniProt P01584
Pathways Signalisation NF-kappaB, Interferon-gamma Pathway, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints
Indications d'application WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Store at -20°C
Date de péremption 12 months
Images (Fournisseur)
ELISA image for anti-Interleukin 1, beta (IL1B) (AA 120-170) antibody (ABIN728503) Antigen: 2 µg/100 µL Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16...
Immunohistochemistry (IHC) image for anti-Interleukin 1, beta (IL1B) (AA 120-170) antibody (ABIN728503) Formalin-fixed and paraffin embedded mouse lung labeled with (ABIN728503) Rabbit Anti...
Immunofluorescence (IF) image for anti-Interleukin 1, beta (IL1B) (AA 120-170) antibody (ABIN728503) Image was kindly submitted by Dr.Rachel Reith, NIH. Paraffin-embedded mouse brain sta...
 image for anti-Interleukin 1, beta (IL1B) (AA 120-170) antibody (ABIN728503) Raw264.7 lysates probed with IL-1 Beta Polyclonal Antibody, Unconjugated at 1:300 di...
Produit citée dans: Ding, Ren, Yu, Yu, Zhou: "Porphyromonas gingivalis, a periodontitis causing bacterium, induces memory impairment and age-dependent neuroinflammation in mice." dans: Immunity & ageing : I & A, Vol. 15, pp. 6, 2018 (PubMed). Méthode utilisée: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Liu, Li, Weng: "Effect of BTXA on Inhibiting Hypertrophic Scar Formation in a Rabbit Ear Model." dans: Aesthetic plastic surgery, Vol. 41, Issue 3, pp. 721-728, 2017 (PubMed). Méthode utilisée: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Échantillon (espèces): Rabbit). Détails: Sample: ear

Liu, Cao, Li, Wang, Zhang, Dong Zhang, Liu, Yuan, Zhan: "Autophagy induced by DAMPs facilitates the inflammation response in lungs undergoing ischemia-reperfusion injury through promoting TRAF6 ubiquitination." dans: Cell death and differentiation, Vol. 24, Issue 4, pp. 683-693, 2017 (PubMed).

Hu, Liu, Deng, Ma, Sheng, Weng, Xu: "Immunoreactivities of IL-1β and IL-1R in oviduct of Chinese brown frog (Rana dybowskii) during pre-hibernation and the breeding period." dans: Acta histochemica, Vol. 118, Issue 2, pp. 164-9, 2016 (PubMed). (Échantillon (espèces): Others).

Du, Niu, Wang, Zhao, Kong, Zhang, Nan: "TLR4‑dependent signaling pathway modulation: A novel mechanism by which pioglitazone protects against nutritional fibrotic steatohepatitis in mice." dans: Molecular medicine reports, Vol. 13, Issue 3, pp. 2159-66, 2016 (PubMed). Méthode utilisée: Western Blotting (WB), Western Blotting (WB) (Échantillon (espèces): Mouse (Murine)). Détails: Sample: liver

Xi, Hu, Guo, Wang, Sheng, Han, Yuan, Weng, Xu: "Immunoreactivities of NF-κB, IL-1β and IL-1R in the skin of Chinese brown frog (Rana dybowskii)." dans: Acta histochemica, Vol. 119, Issue 1, pp. 64-70, 2016 (PubMed). Méthode utilisée: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Échantillon (espèces): Others). Détails: Sample: skin

Heitzer, Kaiser, Kanagaratnam, Zendedel, Hartmann, Beyer, Johann: "Administration of 17β-Estradiol Improves Motoneuron Survival and Down-regulates Inflammasome Activation in Male SOD1(G93A) ALS Mice." dans: Molecular neurobiology, 2016 (PubMed). Méthode utilisée: Western Blotting (WB), Western Blotting (WB) (Échantillon (espèces): Mouse (Murine)). Détails: Sample: spinal cord

Han, Lu, Zhao, Wang, Li, Wang: "Electroacupuncture modulated the inflammatory reaction in MCAO rats via inhibiting the TLR4/NF-κB signaling pathway in microglia." dans: International journal of clinical and experimental pathology, Vol. 8, Issue 9, pp. 11199-205, 2016 (PubMed). Méthode utilisée: ELISA (ELISA), ELISA (ELISA)

Wang, Chen, Li, Ma, Tang: "Anti-inflammatory cytokine TSG-6 inhibits hypertrophic scar formation in a rabbit ear model." dans: European journal of pharmacology, Vol. 751, pp. 42-9, 2015 (PubMed). Méthode utilisée: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Échantillon (espèces): Rabbit).

Johann, Heitzer, Kanagaratnam, Goswami, Rizo, Weis, Troost, Beyer: "NLRP3 inflammasome is expressed by astrocytes in the SOD1 mouse model of ALS and in human sporadic ALS patients." dans: Glia, 2015 (PubMed). Méthode utilisée: Western Blotting (WB) (Échantillon (espèces): Human).

Li, Dan, Nie, Hu, Gesang, Bianba, Ze, Ciren: "CD14 knockdown reduces lipopolysaccharide-induced cell viability and expression of inflammation-associated genes in gastric cancer cells in vitro and in nude mouse xenografts." dans: Molecular medicine reports, Vol. 12, Issue 3, pp. 4332-9, 2015 (PubMed).

de Jesus, Spadacci-Morena, dos Anjos Rabelo, Pinfildi, Fukuda, Plapler: "Low-level laser therapy in IL-1β, COX-2, and PGE2 modulation in partially injured Achilles tendon." dans: Lasers in medical science, Vol. 30, Issue 1, pp. 153-8, 2015 (PubMed). Méthode utilisée: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Échantillon (espèces): Rat (Rattus)). Détails: Sample: tendon

Bagriyanik, Ersoy, Cetinkaya, Ikizoglu, Kutri, Ozcana, Kamanga, Kiray: "The effects of resveratrol on chronic constriction injury of sciatic nerve in rats." dans: Neuroscience letters, Vol. 561, pp. 123-7, 2014 (PubMed). Méthode utilisée: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Échantillon (espèces): Rat (Rattus)).

Zhong, Shu, Wang, Luo, Zhong, Ran, Zheng, Yin, Ling: "Enhanced homing of mesenchymal stem cells to the ischemic myocardium by ultrasound-targeted microbubble destruction." dans: Ultrasonics, Vol. 52, Issue 2, pp. 281-6, 2011 (PubMed). Méthode utilisée: Western Blotting (WB) Détails: Sample: heart

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