Glutamate Receptor 3 anticorps (AA 451-550)

N° du produit ABIN734603

Détail du produit anti-Glutamate Receptor 3 anticorps

Antigène: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Épitope: AA 451-550

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glutamate Receptor 3 est non-conjugé

Application: ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Rat

Homologie: Mouse,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GLUR3

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur Glutamate Receptor 3

Antigène: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Autre désignation: GLUR3/GRIA 3 (GRIA3 Produits)

Synonymes: anticorps AMPA, anticorps gria3, anticorps GRIN3A, anticorps glur3b, anticorps gria3.2, anticorps zfGRIA3[b], anticorps si:bz1o18.1, anticorps SI:zC231H1.1, anticorps si:zc140k5.3, anticorps GLUR3, anticorps GLUR-C, anticorps GLUR3/C, anticorps GRIA3, anticorps glur3, anticorps GluA3, anticorps GluR-3, anticorps GluR-C, anticorps GluR-K3, anticorps GLUR-K3, anticorps GLURC, anticorps MRX94, anticorps 2900064I19Rik, anticorps Glur-3, anticorps Glur3, anticorps Gluralpha3, anticorps glutamate receptor, ionotropic, AMPA 3b, anticorps glutamate ionotropic receptor AMPA type subunit 3, anticorps glutamate receptor, ionotropic, AMPA 3, anticorps glutamate receptor, ionotropic, AMPA 3 L homeolog, anticorps glutamate receptor, ionotropic, AMPA3 (alpha 3), anticorps gria3b, anticorps GRIA3, anticorps gria3, anticorps gria3.L, anticorps Gria3

Sujet:

Synonyms: GLUR3, GLURC, GluA3, MRX94, GLUR-C, GLUR-K3, Glutamate receptor 3, GluR-3, AMPA-selective glutamate receptor 3, Glutamate receptor ionotropic, AMPA 3, GRIA3

Background: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

ID gène: 2892

UniProt: P42263

Pathways: Signalisation PI3K-Akt, cAMP Metabolic Process, Synaptic Membrane