MMP12 anticorps (Matrix Metallopeptidase 12 (Macrophage Elastase))

Details for Product anti-MMP12 Antibody No. ABIN735413
Antigène
Reactivité
Humain, Souris, Rat (Rattus)
161
58
51
6
1
Hôte
Lapin
184
8
4
3
2
Clonalité
Polyclonal
Conjugué
Cet anticorp MMP12 est non-conjugé
23
17
7
4
4
4
4
4
4
3
3
3
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
165
70
68
21
15
14
13
12
10
8
3
2
1
Options
Immunogène KLH conjugated synthetic peptide derived from rat MMP12
Isotype IgG
Purification Purified by Protein A.
Antigène
Autre désignation Mmp-12 (MMP12 Antibody Extrait)
Sujet

May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3 (By similarity).

Subcellular location: Extracellular, Secreted

Synonyms: Mme, Macrophage metalloelastase, Matrix metalloproteinase-12, MMP-12, Mmp12, Mmel

ID gène 117033
UniProt Q63341
Indications d'application WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Store at -20°C
Date de péremption 12 months
Images (Fournisseur)
Image no. 1 for anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) antibody (ABIN735413) Formalin-fixed and paraffin embedded mouse ovarian tissue labeled with Anti-MMP-12, U...
Produit citée dans: Hashimoto, Zaima, Sekiguchi, Kugo, Miyamoto, Hoshino, Kawasaki, Sutoh, Usumi, Moriyama: "Dietary DNA Attenuates the Degradation of Elastin Fibers in the Aortic Wall in Nicotine-Administrated Mice." dans: Journal of nutritional science and vitaminology, Vol. 64, Issue 4, pp. 271-276, 2019 (PubMed). Méthode utilisée: Immunohistochemistry (IHC), Immunohistochemistry (IHC)

Kugo, Zaima, Onozato, Miyamoto, Hashimoto, Yanagimoto, Moriyama: "Suppressive effects of dietary EPA-rich fish oil on the degradation of elastin fibers in the aortic wall in nicotine-administered mice." dans: Food & function, Vol. 8, Issue 8, pp. 2829-2835, 2017 (PubMed). Méthode utilisée: Immunohistochemistry (Frozen Sections) (IHC (fro)) (Échantillon (espèces): Mouse (Murine)). Détails: Sample: aortic