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CCL2 anticorps (AA 61-148)

CCL2 Reactivité: Humain, Souris, Rat WB, ELISA, IHC (p), IF (p), IHC (fro), IF (cc) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN737676
  • Antigène Voir toutes CCL2 Anticorps
    CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
    Épitope
    • 24
    • 15
    • 13
    • 10
    • 8
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 61-148
    Reactivité
    • 104
    • 65
    • 62
    • 18
    • 18
    • 18
    • 16
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 118
    • 62
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    Lapin
    Clonalité
    • 134
    • 73
    Polyclonal
    Conjugué
    • 113
    • 39
    • 14
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp CCL2 est non-conjugé
    Application
    • 140
    • 74
    • 57
    • 29
    • 27
    • 24
    • 24
    • 18
    • 16
    • 14
    • 14
    • 13
    • 13
    • 12
    • 11
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc))
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from rat MCP-1
    Isotype
    IgG
    Top Product
    Discover our top product CCL2 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Li, Fang, Tian, Wang, Ao, Hou, Tong, Fan, Bai: "Curcumin attenuates the development of thoracic aortic aneurysm by inhibiting VEGF expression and inflammation." dans: Molecular medicine reports, Vol. 16, Issue 4, pp. 4455-4462, (2018) (PubMed).

    Kugo, Zaima, Onozato, Miyamoto, Hashimoto, Yanagimoto, Moriyama: "Suppressive effects of dietary EPA-rich fish oil on the degradation of elastin fibers in the aortic wall in nicotine-administered mice." dans: Food & function, Vol. 8, Issue 8, pp. 2829-2835, (2017) (PubMed).

    Kuracha, Thomas, Loggie, Govindarajan: "Patient-derived xenograft mouse models of pseudomyxoma peritonei recapitulate the human inflammatory tumor microenvironment." dans: Cancer medicine, Vol. 5, Issue 4, pp. 711-9, (2016) (PubMed).

    Jeong, Lee, Kim, Yang, Sung, Seong: "Irradiation-induced localization of IL-12-expressing mesenchymal stem cells to enhance the curative effect in murine metastatic hepatoma." dans: International journal of cancer. Journal international du cancer, Vol. 137, Issue 3, pp. 721-30, (2015) (PubMed).

    Guo, Feng, Yao, Sun, Zhu: "Transplantation of endothelial progenitor cells in treating rats with IgA nephropathy." dans: BMC nephrology, Vol. 15, pp. 110, (2014) (PubMed).

    Iwasa, Arakaki, Honma, Ushio, Yamada, Kondo, Kurosawa, Kujiraoka, Tsunematsu, Kudo, Tanaka, Yoshimura, Harada, Hayashi, Ishimaru: "Aromatase controls Sjögren syndrome-like lesions through monocyte chemotactic protein-1 in target organ and adipose tissue-associated macrophages." dans: The American journal of pathology, Vol. 185, Issue 1, pp. 151-61, (2014) (PubMed).

    Su, Zhou, Wang, Yang, Li, Yu, Li: "The PPARβ/δ agonist GW501516 attenuates peritonitis in peritoneal fibrosis via inhibition of TAK1-NFκB pathway in rats." dans: Inflammation, Vol. 37, Issue 3, pp. 729-37, (2014) (PubMed).

    Guo, Zhang, Li, Xu: "Effect of telmisartan on the expression of adiponectin receptors and nicotinamide adenine dinucleotide phosphate oxidase in the heart and aorta in type 2 diabetic rats." dans: Cardiovascular diabetology, Vol. 11, pp. 94, (2012) (PubMed).

  • Antigène
    CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
    Autre désignation
    MCP1 (CCL2 Produits)
    Synonymes
    anticorps GDCF-2, anticorps HC11, anticorps HSMCR30, anticorps MCAF, anticorps MCP-1, anticorps MCP1, anticorps SCYA2, anticorps SMC-CF, anticorps AI323594, anticorps JE, anticorps Scya2, anticorps Sigje, anticorps MCP-1A, anticorps MCP1A, anticorps C-C motif chemokine ligand 2, anticorps chemokine (C-C motif) ligand 2, anticorps C-C motif chemokine 2, anticorps CCL2, anticorps Ccl2, anticorps LOC101120093
    Sujet

    Synonyms: MCP-1, Scya2, Sigje, C-C motif chemokine 2, Immediate-early serum-responsive protein JE, Monocyte chemoattractant protein 1, Monocyte chemotactic protein 1, Small-inducible cytokine A2, Ccl2, Je, Mcp1

    Background: Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. Monomer or homodimer, in equilibrium. Binds to CCR2 and CCR4. Is tethered on endothelial cells by glycosaminoglycan (GAG) side chains of proteoglycans. Processing at the N-terminus can regulate receptor and targetcell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant. Genetic variations in CCL2 determine Mycobacterium tuberculosis susceptibility Belongs to the intercrine beta (chemokine CC) family. The MCP-1( the monocyte chemotactic protein1) has many pits that regulates the function toward sex to turn to record the factor, it can induce to have relation with inflammation with the immunity various genes turn to record.The immunity MCP-1 set turns the male signal to mainly locate the afterbirth syrup inside.

    ID gène
    24770
    UniProt
    P14844
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, Phosphorylation & l'infection par le SRAS-CoV-2
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