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SPARC anticorps (AA 101-200)

SPARC Reactivité: Humain, Souris, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN738141
  • Antigène Voir toutes SPARC Anticorps
    SPARC (Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC))
    Épitope
    • 14
    • 12
    • 12
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    Reactivité
    • 90
    • 44
    • 39
    • 13
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 84
    • 22
    • 4
    • 2
    • 2
    Lapin
    Clonalité
    • 88
    • 26
    Polyclonal
    Conjugué
    • 64
    • 15
    • 9
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SPARC est non-conjugé
    Application
    • 98
    • 48
    • 39
    • 23
    • 12
    • 12
    • 10
    • 10
    • 9
    • 9
    • 8
    • 6
    • 5
    • 5
    • 5
    • 3
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain, Souris, Rat
    Homologie
    Dog,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human SPARC
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Zong, Zeng, Zou, Li, Fang, Lu, Xiao, Zhang: "Effects of Polygonatum sibiricum polysaccharide on the osteogenic differentiation of bone mesenchymal stem cells in mice." dans: International journal of clinical and experimental pathology, Vol. 8, Issue 6, pp. 6169-80, (2015) (PubMed).

    Kurtul, Eroglu, Unal, Tasdemir, Orhan, Zararsiz, Baran, Kaplan, Kontas: "Prognostic Value of SPARC Expression in Unresectable NSCLC Treated with Concurrent Chemoradiotherapy." dans: Asian Pacific journal of cancer prevention : APJCP, Vol. 15, Issue 20, pp. 8911-6, (2014) (PubMed).

    Chen, Wang, Xi, Xue, He, Zhang, Zhao: "SPARC is a key regulator of proliferation, apoptosis and invasion in human ovarian cancer." dans: PLoS ONE, Vol. 7, Issue 8, pp. e42413, (2012) (PubMed).

  • Antigène
    SPARC (Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC))
    Autre désignation
    SPARC (SPARC Produits)
    Synonymes
    anticorps ON, anticorps AA517111, anticorps BM-40, anticorps hm:zeh0062, anticorps SPARC, anticorps sparc, anticorps secreted protein acidic and cysteine rich, anticorps secreted acidic cysteine rich glycoprotein, anticorps secreted protein, acidic, cysteine-rich (osteonectin), anticorps secreted protein, acidic, cysteine-rich (osteonectin) L homeolog, anticorps secreted protein, acidic, cysteine-rich (osteonectin) S homeolog, anticorps SPARC, anticorps Sparc, anticorps sparc, anticorps sparc.L, anticorps sparc.S
    Sujet

    Synonyms: ON, SPARC, Basement-membrane protein 4, BM-4, Osteonectin, Secreted protein acidic and rich in cysteine

    Background: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites, an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.

    ID gène
    6678
    UniProt
    P09486
    Pathways
    Autophagy
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