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SSTR2 anticorps (AA 211-320)

SSTR2 Reactivité: Humain, Souris WB, ELISA, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN738216
  • Antigène Voir toutes SSTR2 Anticorps
    SSTR2 (Somatostatin Receptor 2 (SSTR2))
    Épitope
    • 9
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 211-320
    Reactivité
    • 45
    • 26
    • 26
    • 10
    • 9
    • 9
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    Humain, Souris
    Hôte
    • 42
    • 4
    Lapin
    Clonalité
    • 40
    • 5
    • 1
    Polyclonal
    Conjugué
    • 35
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SSTR2 est non-conjugé
    Application
    • 21
    • 15
    • 12
    • 9
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain, Souris
    Homologie
    Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit,Guinea Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human SSTR2
    Isotype
    IgG
    Top Product
    Discover our top product SSTR2 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Sakai, Yonezawa, Yamawaki, Oyamada: "Alteration of somatostatin receptor 2 expression in canine mammary gland tumor." dans: The Journal of veterinary medical science / the Japanese Society of Veterinary Science, (2015) (PubMed).

    Ruan, Yu, Xu, Zhang, Long, Shen: "Attenuation of stress-induced gastrointestinal motility disorder by gentiopicroside, from Gentiana macrophylla Pall." dans: Fitoterapia, Vol. 103, pp. 265-76, (2015) (PubMed).

  • Antigène
    SSTR2 (Somatostatin Receptor 2 (SSTR2))
    Autre désignation
    SSTR2/Somatostatin Receptor 2 (SSTR2 Produits)
    Synonymes
    anticorps Smstr2, anticorps SSTR-2, anticorps Smstr-2, anticorps sst2, anticorps SS2R, anticorps SSTR2, anticorps MGC80373, anticorps somatostatin receptor 2, anticorps somatostatin receptor 2 L homeolog, anticorps SSTR2, anticorps Sstr2, anticorps sstr2.L
    Sujet

    Synonyms: Somatostatin receptor type 2, SS-2-R, SS2-R, SS2R, SRIF-1, SSTR2

    Background: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

    ID gène
    6752
    UniProt
    P30874
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