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ASCL1 anticorps (AA 151-236)

ASCL1 Reactivité: Humain, Souris, Rat ELISA, WB, IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN738471
  • Antigène Voir toutes ASCL1 Anticorps
    ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
    Épitope
    • 21
    • 14
    • 9
    • 8
    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-236
    Reactivité
    • 84
    • 44
    • 27
    • 9
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 84
    • 6
    • 2
    Lapin
    Clonalité
    • 86
    • 6
    Polyclonal
    Conjugué
    • 40
    • 11
    • 9
    • 9
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ASCL1 est non-conjugé
    Application
    • 79
    • 59
    • 28
    • 12
    • 12
    • 11
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain, Souris, Rat
    Homologie
    Cow,Sheep
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human ASCL1
    Isotype
    IgG
    Top Product
    Discover our top product ASCL1 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Misra, Luo, Li, Matise, Xiang: "Asymmetric activation of Dll4-Notch signaling by Foxn4 and proneural factors activates BMP/TGFβ signaling to specify V2b interneurons in the spinal cord." dans: Development (Cambridge, England), Vol. 141, Issue 1, pp. 187-98, (2014) (PubMed).

  • Antigène
    ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
    Autre désignation
    ASCL1 (ASCL1 Produits)
    Synonymes
    anticorps ASH1, anticorps HASH1, anticorps MASH1, anticorps bHLHa46, anticorps AI225900, anticorps Mash1, anticorps ASCL1, anticorps Zash-1a, anticorps ash, anticorps asha, anticorps id:ibd5085, anticorps im:7138587, anticorps si:dkey-264k15.2, anticorps zash1a, anticorps zasha, anticorps Xash1, anticorps ascl1-A, anticorps Zash-1b, anticorps ashb, anticorps zashb, anticorps achaete-scute family bHLH transcription factor 1, anticorps achaete-scute family bHLH transcription factor 1a, anticorps achaete-scute family bHLH transcription factor 1 L homeolog, anticorps achaete-scute complex homolog 1, anticorps achaete-scute family bHLH transcription factor 1b, anticorps ASCL1, anticorps Ascl1, anticorps ascl1a, anticorps ascl1.L, anticorps LOC100220505, anticorps ascl1b
    Sujet

    Synonyms: ASH1, HASH1, MASH1, bHLHa46, Achaete-scute homolog 1, ASH-1, Class A basic helix-loop-helix protein 46, ASCL1

    Background: Transcription factor that controls transcriptional expression of its target genes by binding to the E box (5'-CANNTG-3'). Plays a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Acts synergistically with FOXN4 to specify the identity of V2b neurons rather than V2a from bipotential p2 progenitors during spinal cord neurogenesis, probably through DLL4-NOTCH signaling activation. Essential for the generation of olfactory and autonomic neurons (By similarity).

    ID gène
    429
    UniProt
    P50553
    Pathways
    Dopaminergic Neurogenesis
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