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TRAF6 anticorps (AA 441-530)

TRAF6 Reactivité: Humain, Souris, Rat, Poulet WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN738906
  • Antigène Voir toutes TRAF6 Anticorps
    TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))
    Épitope
    • 14
    • 9
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 441-530
    Reactivité
    • 58
    • 31
    • 25
    • 14
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Humain, Souris, Rat, Poulet
    Hôte
    • 56
    • 5
    • 2
    Lapin
    Clonalité
    • 54
    • 9
    Polyclonal
    Conjugué
    • 40
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TRAF6 est non-conjugé
    Application
    • 59
    • 17
    • 14
    • 12
    • 12
    • 11
    • 11
    • 10
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Poulet, Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from mouse TRAF6
    Isotype
    IgG
    Top Product
    Discover our top product TRAF6 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Li, Yu, Li, Liu, Jiao, Song, Lv, Qin: "Phycocyanin attenuates pulmonary fibrosis via the TLR2-MyD88-NF-κB signaling pathway." dans: Scientific reports, Vol. 7, Issue 1, pp. 5843, (2017) (PubMed).

  • Antigène
    TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))
    Autre désignation
    TRAF6 (TRAF6 Produits)
    Synonymes
    anticorps MGC:3310, anticorps RNF85, anticorps 2310003F17Rik, anticorps AI851288, anticorps C630032O20Rik, anticorps rnf85, anticorps traf6, anticorps xtraf6, anticorps CG10961, anticorps DTRAF2, anticorps Dmel\\CG10961, anticorps TRAF, anticorps TRAF2, anticorps TRAF6, anticorps Traf2, anticorps dTRAF2, anticorps dTRAF6, anticorps dTraf2, anticorps dtraf2, anticorps GB10539, anticorps fi15f02, anticorps wu:fi15f02, anticorps zgc:63704, anticorps TNF receptor associated factor 6, anticorps TNF receptor-associated factor 6, anticorps TNF receptor associated factor 6 L homeolog, anticorps TNF-receptor-associated factor 6, anticorps TNF receptor associated factor 6 S homeolog, anticorps TRAF6, anticorps Traf6, anticorps traf6.L, anticorps traf6, anticorps LOC551819, anticorps traf6.S
    Sujet

    Synonyms: AI851288, 2310003F17Rik, C630032O20Rik, TNF receptor-associated factor 6, E3 ubiquitin-protein ligase TRAF6, Traf6

    Background: E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation (By similarity). Leads to the activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to play a role in signal transduction initiated via TNF receptor, IL-1 receptor and IL-17 receptor. Regulates osteoclast differentiation by mediating the activation of adapter protein complex 1 (AP-1) and NF-kappa-B, in response to RANK-L stimulation. Together with MAP3K8, mediates CD40 signals that activate ERK in B-cells and macrophages, and thus may play a role in the regulation of immunoglobulin production.

    ID gène
    22034
    UniProt
    P70196
    Pathways
    Signalisation NF-kappaB, TCR Signaling, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Hepatitis C, Toll-Like Receptors Cascades, Ubiquitin Proteasome Pathway
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