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Influenza A Matrix Protein 2 anticorps (Influenza A Virus) (AA 2-60) (Biotin)

M2 Reactivité: Influenza A Virus, Virus ELISA, IHC (fro), IHC (p) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN739061
  • Antigène Voir toutes Influenza A Matrix Protein 2 (M2) Anticorps
    Influenza A Matrix Protein 2 (M2)
    Épitope
    • 14
    • 6
    AA 2-60
    Reactivité
    • 15
    • 14
    • 2
    • 1
    • 1
    • 1
    Influenza A Virus, Virus
    Hôte
    • 20
    Lapin
    Clonalité
    • 20
    Polyclonal
    Conjugué
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Biotin
    Application
    • 13
    • 13
    • 7
    • 3
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificité
    This antibody will recognize many Influenza A virus strains
     Réactivité croisée
    Virus
    Réactivité croisée (Details)
    Influenza A virus
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from Influenza A virus H5N1 Matrix Protein-2
    Isotype
    IgG
    Top Product
    Discover our top product M2 Anticorps primaire
  • Indications d'application
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    Influenza A Matrix Protein 2 (M2)
    Autre désignation
    Influenza A virus Matrix Protein 2 (M2 Produits)
    Synonymes
    anticorps matrix protein 2
    Classe de substances
    Influenza Protein
    Sujet

    Synonyms: Avian influenza Matrix Protein-2, Influenza A virus H7N7 H9N2 H13N6 H16N3 H1N1 N2N1 H3N2 H2N2

    Background: Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of the endosome triggers M2 ion channel activity. The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur. Also plays a role in viral proteins secretory pathway. Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation

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