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Histone 3 anticorps (AA 71-136)

H3 Reactivité: Humain, Souris, Rat WB, ELISA, ICC, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN739109
  • Antigène Voir toutes Histone 3 (H3) Anticorps
    Histone 3 (H3)
    Épitope
    • 63
    • 47
    • 46
    • 45
    • 41
    • 37
    • 36
    • 35
    • 35
    • 35
    • 34
    • 31
    • 31
    • 29
    • 29
    • 29
    • 26
    • 25
    • 23
    • 23
    • 23
    • 22
    • 20
    • 18
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    • 16
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    • 12
    • 12
    • 12
    • 12
    • 12
    • 11
    • 11
    • 10
    • 10
    • 10
    • 9
    • 9
    • 8
    AA 71-136
    Reactivité
    • 1404
    • 941
    • 861
    • 59
    • 42
    • 41
    • 41
    • 40
    • 39
    • 35
    • 35
    • 30
    • 30
    • 22
    • 19
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 1214
    • 247
    • 12
    • 4
    Lapin
    Clonalité
    • 1120
    • 356
    • 1
    Polyclonal
    Conjugué
    • 820
    • 81
    • 65
    • 64
    • 63
    • 63
    • 63
    • 62
    • 37
    • 33
    • 24
    • 17
    • 17
    • 17
    • 17
    • 17
    • 14
    • 2
    • 1
    Cet anticorp Histone 3 est non-conjugé
    Application
    • 1055
    • 410
    • 378
    • 312
    • 250
    • 187
    • 185
    • 179
    • 162
    • 161
    • 141
    • 127
    • 118
    • 47
    • 38
    • 34
    • 32
    • 20
    • 16
    • 14
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain, Souris, Rat
    Homologie
    Cow,Pig,Rabbit,Drosophila
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Histone H3
    Isotype
    IgG
    Top Product
    Discover our top product H3 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Si, Meng, Gao, Hui, Li, Liu, Yang: "Linagliptin protects rat carotid artery from balloon injury and activates the NRF2 antioxidant pathway." dans: Experimental animals, Vol. 68, Issue 1, pp. 81-90, (2019) (PubMed).

    Zhang, Zhang, Li, Wang, Gu, Feng, Wei, Peng, Zhang, Su, Wang, Li, Yang, Wong, Yang, Ma: "Uncoupling Protein 2 Inhibits Myointimal Hyperplasia in Preclinical Animal Models of Vascular Injury." dans: Journal of the American Heart Association, Vol. 6, Issue 10, (2018) (PubMed).

    Joy, Gau, Castellucci, Prywes, Roy: "The myocardin-related transcription factor MKL co-regulates the cellular levels of two profilin isoforms." dans: The Journal of biological chemistry, Vol. 292, Issue 28, pp. 11777-11791, (2017) (PubMed).

    Yang, Liu, Jiang, Wang, Zhang: "Celastrol Attenuates Multiple Sclerosis and Optic Neuritis in an Experimental Autoimmune Encephalomyelitis Model." dans: Frontiers in pharmacology, Vol. 8, pp. 44, (2017) (PubMed).

    Shen, Wu, Liu, Zhao, Zhao: "Epigallocatechin-3-gallate alleviates paraquat-induced acute lung injury and inhibits upregulation of toll-like receptors." dans: Life sciences, Vol. 170, pp. 25-32, (2016) (PubMed).

    Qian, Zhang, Hu, Xu, Chen, Hu, Zhao, Liu: "Silver nanoparticle-induced hemoglobin decrease involves alteration of histone 3 methylation status." dans: Biomaterials, Vol. 70, pp. 12-22, (2015) (PubMed).

    Duan, Liu, Liang, Yang, Xia, Wang, Chen, Yu: "Oestrogen receptor-mediated expression of Olfactomedin 4 regulates the progression of endometrial adenocarcinoma." dans: Journal of cellular and molecular medicine, Vol. 18, Issue 5, pp. 863-74, (2014) (PubMed).

    Tang, Chen, Liang, Rong, Yao, Yang, Wu: "Selective antegrade cerebral perfusion attenuating the TLR4/NF-?B pathway during deep hypothermia circulatory arrest in a pig model." dans: Cardiology, Vol. 128, Issue 3, pp. 243-50, (2014) (PubMed).

    Wang, Ma, Su: "NF-?B pathway contributes to cadmium-induced apoptosis of porcine granulosa cells." dans: Biological trace element research, Vol. 153, Issue 1-3, pp. 403-10, (2013) (PubMed).

    Liu, Ji, Zhang, Tong, Pan, Liu, Zhang, Huang, Su, Willard, Zheng: "Nonenzymatic glycation of high-density lipoprotein impairs its anti-inflammatory effects in innate immunity." dans: Diabetes/metabolism research and reviews, Vol. 28, Issue 2, pp. 186-95, (2012) (PubMed).

    Zhou, Zhou, Wang, Mu, Wu, Guo, Zhang, Wu: "Epigallocatechin-3-gallate inhibits proliferation and migration of human colon cancer SW620 cells in vitro." dans: Acta pharmacologica Sinica, Vol. 33, Issue 1, pp. 120-6, (2012) (PubMed).

  • Antigène
    Histone 3 (H3)
    Autre désignation
    Histone H3 (H3 Produits)
    Synonymes
    anticorps H-3, anticorps histocompatibility 3, anticorps H3
    Sujet

    Synonyms: Histone H3, H3.1, HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, H3FA, H3FL, H3FC, H3FB, H3FD, H3FI, H3FH, H3FK, H3FF, H3FJ, H3.2, HIST2H3A, HIST2H3C, HIST2H3D, H3F2, H3FM, H3.3, H3F3A, H3F3B, H3.3A, H3.3B, H3F3, PP781, H3.3C, H3F3C, H3.5, H3.1t, HIST3H3, H3FT

    Background: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

    ID gène
    3020
    UniProt
    P84243
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