Recombinant Retinoid X Receptor alpha anticorps

N° du produit ABIN7828527

Cet anticorps anti-Retinoid X Receptor alpha Monoclonal Lapin (Clone A659) (ABIN7828527) détecte spécifiquement Retinoid X Receptor alpha dans WB et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant Retinoid X Receptor alpha anticorps (ABIN7828527)

Antigène: Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Retinoid X Receptor alpha est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: A659

Détail du produit anti-Retinoid X Receptor alpha anticorps

Fonction: Recombinant RXRA Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human RXRA fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:1000,IF 1:50

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur Retinoid X Receptor alpha

Antigène: Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))

Autre désignation: RXRA

Sujet: NR2B,NR2B1,RXRA,Retinoid X receptor alpha,Retinoid X receptor α (RXRA) is the founding RXR family member and is predominantly expressed in the liver, kidney, epidermis, intestine, and a variety of tissues. Knockout of the murine rxrα gene results in embryonic lethality tentatively due to myocardial hypoplasia, which demonstrates the importance of RXRA in retinoid signalingin vivo. Biochemical evidence suggests that RXRA transcriptional activity is post-translationally regulated through the Ras-Raf-MAPK signaling cascade. MAPK-dependent phosphorylation of RXRα directly abrogates the ability of RXRA to associate with nuclear receptor coactivators. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 51 kDa

Observed MW: 56 kDa The actual band is not consistent with the expectation.

UniProt: P19793

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Hepatitis C