CYP1A2 anticorps (AA 221-320)

N° du produit ABIN742470

Détail du produit anti-CYP1A2 anticorps

Antigène: CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))

Épitope: AA 221-320

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP1A2 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Cytochrome P450 1A2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-CYP1A2 (ABIN742470)

Huang, Duan, Zhao, Gao, Niu, Xu, Li: "Reduction of Aflatoxin B1 Toxicity by Lactobacillus plantarum C88: A Potential Probiotic Strain Isolated from Chinese Traditional Fermented Food "Tofu"." dans: PLoS ONE, Vol. 12, Issue 1, pp. e0170109, (2017) (PubMed).

Détails sur CYP1A2

Antigène: CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))

Autre désignation: Cytochrome P450 1A2 (CYP1A2 Produits)

Synonymes: anticorps CP12, anticorps P3-450, anticorps P450(PA), anticorps CYP1A2, anticorps CYPIA2, anticorps P450-PM4, anticorps Cyp1a1, anticorps P450-3, anticorps CYPD45, anticorps P-450d, anticorps RATCYPD45, anticorps CYP1A5, anticorps CP450, anticorps CYP-IA2, anticorps cytochrome P450 family 1 subfamily A member 2, anticorps cytochrome P450 1A2, anticorps cytochrome P450 LM4, anticorps cytochrome P450, family 1, subfamily A, polypeptide 2, anticorps cytochrome P450, family 1, subfamily a, polypeptide 2, anticorps cytochrome P450 1A2-like, anticorps CYP1A2, anticorps LOC100328937, anticorps Cyp1a2, anticorps VDBG_06455, anticorps LOC101825565, anticorps LOC102130662

Sujet:

Synonyms: CP12, P3-450, P450(PA), Cytochrome P450 1A2, CYPIA2, Cytochrome P(3)450, Cytochrome P450 4, Cytochrome P450-P3, CYP1A2

Background: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin.

ID gène: 1544

UniProt: P05177