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SPHK1 anticorps (AA 1-100)

SPHK1 Reactivité: Humain, Souris, Rat WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN748598
  • Antigène Voir toutes SPHK1 Anticorps
    SPHK1 (Sphingosine Kinase 1 (SPHK1))
    Épitope
    • 14
    • 14
    • 9
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reactivité
    • 104
    • 43
    • 37
    • 11
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 95
    • 9
    • 1
    Lapin
    Clonalité
    • 91
    • 14
    Polyclonal
    Conjugué
    • 55
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SPHK1 est non-conjugé
    Application
    • 75
    • 45
    • 25
    • 18
    • 13
    • 12
    • 12
    • 10
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain, Souris, Rat
    Homologie
    Dog,Cow,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human SPHK1
    Isotype
    IgG
    Top Product
    Discover our top product SPHK1 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Tran, Jersmann, Truong, Hamon, Roscioli, Ween, Pitman, Pitson, Hodge, Reynolds, Hodge: "Disrupted epithelial/macrophage crosstalk via Spinster homologue 2-mediated S1P signaling may drive defective macrophage phagocytic function in COPD." dans: PLoS ONE, Vol. 12, Issue 11, pp. e0179577, (2017) (PubMed).

    Tani, Tabuchi, Hara: "Hair Cell Loss Induced by Sphingosine and a Sphingosine Kinase Inhibitor in the Rat Cochlea." dans: Neurotoxicity research, Vol. 29, Issue 1, pp. 35-46, (2016) (PubMed).

    Tran, Barnawi, Ween, Hamon, Roscioli, Hodge, Reynolds, Pitson, Davies, Haberberger, Hodge: "Cigarette smoke inhibits efferocytosis via deregulation of sphingosine kinase signaling: reversal with exogenous S1P and the S1P analogue FTY720." dans: Journal of leukocyte biology, Vol. 100, Issue 1, pp. 195-202, (2016) (PubMed).

  • Antigène
    SPHK1 (Sphingosine Kinase 1 (SPHK1))
    Autre désignation
    SPHK1 (SPHK1 Produits)
    Synonymes
    anticorps CG1747, anticorps Dmel\\CG1747, anticorps SK1, anticorps Sphk1, anticorps SPHK1, anticorps F18E5.160, anticorps F18E5_160, anticorps sphingosine kinase 1, anticorps SPHK, anticorps 1110006G24Rik, anticorps Sk1, anticorps Spk1, anticorps Sphingosine kinase 1, anticorps sphingosine kinase 1, anticorps sphingosine kinase 1 L homeolog, anticorps Sk1, anticorps SPHK1, anticorps sphk1.L, anticorps Sphk1
    Sujet

    Synonyms: SPHK, Sphingosine kinase 1, SK 1, SPK 1, SPHK1, SPK

    Background: Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as D,L-threo-dihydrosphingosine, N,N-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol.

    ID gène
    8877
    UniProt
    Q9NYA1
    Pathways
    VEGF Signaling
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