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DIO3 anticorps (AA 51-150)

DIO3 Reactivité: Humain WB, ELISA, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN750883
  • Antigène Voir toutes DIO3 Anticorps
    DIO3 (Deiodinase, Iodothyronine, Type III (DIO3))
    Épitope
    • 10
    • 7
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    Reactivité
    • 38
    • 25
    • 18
    Humain
    Hôte
    • 48
    • 1
    Lapin
    Clonalité
    • 48
    • 1
    Polyclonal
    Conjugué
    • 18
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DIO3 est non-conjugé
    Application
    • 39
    • 24
    • 15
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain
    Homologie
    Mouse,Rat,Dog,Cow,Sheep,Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Dio3
    Isotype
    IgG
    Top Product
    Discover our top product DIO3 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    DIO3 (Deiodinase, Iodothyronine, Type III (DIO3))
    Autre désignation
    Dio3 (DIO3 Produits)
    Synonymes
    anticorps 5DIII, anticorps DIOIII, anticorps txdi3, anticorps dioiii, anticorps XL-15, anticorps itdi3, anticorps D3, anticorps TXDI3, anticorps iodothyronine deiodinase 3, anticorps deiodinase, iodothyronine, type 3, anticorps deiodinase, iodothyronine, type III, anticorps deiodinase, iodothyronine type III, anticorps deiodinase, iodothyronine, type 3 L homeolog, anticorps DIO3, anticorps dio3, anticorps Dio3, anticorps dio3.L
    Sujet

    Synonyms: Type 3 DI, D3, 5DIII, Deiodinase iodothyronine type 3, Deiodinase iodothyronine type III, Dio 3, DIOIII, MGC124117, MGC124118, TXDI3, Type III 5' deiodinase, Type III iodothyronine deiodinase, IOD3_HUMAN.

    Background: Dio3 belongs to the iodothyronine deiodinase family. It has an essential role for regulation of thyroid hormone inactivation during embryological development in that it catalyzes the inactivation of thyroid hormone by inner ring deiodination of the prohormone thyroxine (T4) and the bioactive hormone 3,3',5-triiodothyronine (T3) to inactive metabolites, 3,3',5'-triiodothyronine (RT3) and 3,3'-diiodothyronine (T2), respectively. Dio3 may play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones and has been linked to the development of consumptive hypothyroidism in both infants and adults.

    ID gène
    1735
    Pathways
    Hormone Activity
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