Calreticulin anticorps (AA 101-200)

N° du produit ABIN759731

Détail du produit anti-Calreticulin anticorps

Antigène: Calreticulin (CALR)

Épitope: AA 101-200

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Calreticulin est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Pig,Horse,Chicken,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Calreticulin

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-Calreticulin (ABIN759731)

Tanaka, Kataoka, Yano, Sawada, Akashi, Inoue, Suzuki, Inagaki, Hayashi, Nishie, Shimura, Mizoshita, Mori, Kubota, Tanida, Takahashi, Joh: "Immunogenic cell death due to a new photodynamic therapy (PDT) with glycoconjugated chlorin (G-chlorin)." dans: Oncotarget, Vol. 7, Issue 30, pp. 47242-47251, (2016) (PubMed).

Chen, Wu, Xu, Xu: "Calreticulin Binds to Fas Ligand and Inhibits Neuronal Cell Apoptosis Induced by Ischemia-Reperfusion Injury." dans: BioMed research international, Vol. 2015, pp. 895284, (2015) (PubMed).

Angelova, Grekova, Heller, Kuhlmann, Soyka, Giese, Aprahamian, Bour, Rüffer, Cziepluch, Daeffler, Rommelaere, Werner, Raykov, Giese: "Complementary induction of immunogenic cell death by oncolytic parvovirus H-1PV and gemcitabine in pancreatic cancer." dans: Journal of virology, Vol. 88, Issue 10, pp. 5263-76, (2014) (PubMed).

Détails sur Calreticulin

Antigène: Calreticulin (CALR)

Autre désignation: Calreticulin (CALR Produits)

Sujet:

Synonyms: RO, CRT, SSA, cC1qR, HEL-S-99n, Calreticulin, CRP55, Calregulin, Endoplasmic reticulum resident protein 6, ERp6, HACBP, grp6, CALR, CRTC

Background: Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity).

ID gène: 811

UniProt: P27797

Pathways: Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response