FCGR2B anticorps (pTyr292)

N° du produit ABIN761411

Détail du produit anti-FCGR2B anticorps

Antigène: FCGR2B (Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B))

Épitope: pTyr292

Reactivité: Humain, Souris, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FCGR2B est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Singe, Souris

Homologie: Rat,Dog,Sheep,Pig,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human CD32B around the phosphorylation site of Tyr292.

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur FCGR2B

Antigène: FCGR2B (Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B))

Autre désignation: CD32B (FCGR2B Produits)

Synonymes: anticorps CD32, anticorps CD32B, anticorps FCG2, anticorps FCGR2, anticorps IGFR2, anticorps FCGR2B, anticorps AI528646, anticorps F630109E10Rik, anticorps Fc[g]RII, anticorps FcgRII, anticorps Fcgr2, anticorps Fcgr2a, anticorps Fcr-2, anticorps Fcr-3, anticorps Ly-17, anticorps Ly-m20, anticorps LyM-1, anticorps Lym-1, anticorps FCRII, anticorps FcRII, anticorps Fc fragment of IgG receptor IIb, anticorps Fc fragment of IgG, low affinity IIb, receptor (CD32), anticorps Fc receptor, IgG, low affinity IIb, anticorps low affinity immunoglobulin gamma Fc region receptor II, anticorps FCGR2B, anticorps Fcgr2b, anticorps LOC100856270

Sujet:

Synonyms: CD32, FCG2, CD32B, FCGR2, IGFR2, Low affinity immunoglobulin gamma Fc region receptor II-b, IgG Fc receptor II-b, CDw32, Fc-gamma RII-b, Fc-gamma-RIIb, FcRII-b, FCGR2B

Background: Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.

ID gène: 2213

UniProt: P31994

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, BCR Signaling