ZIP2 anticorps (N-Term)

N° du produit ABIN783797

Détail du produit anti-ZIP2 anticorps

Antigène: ZIP2 (Slc39a2) (Solute Carrier Family 39 (Zinc Transporter), Member 2 (Slc39a2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZIP2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects Zinc transporter ZIP2 / SLC39A2 at N-term.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 17 amino acid peptide near the amino terminus of human ZIP2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur ZIP2

Antigène: ZIP2 (Slc39a2) (Solute Carrier Family 39 (Zinc Transporter), Member 2 (Slc39a2))

Autre désignation: Zinc Transporter ZIP2 / SLC39A2 (Slc39a2 Produits)

Synonymes: anticorps 6A1, anticorps ETI-1, anticorps ZIP-2, anticorps ZIP2, anticorps F730005G13Rik, anticorps Gm1789, anticorps Gm289, anticorps Zip2, anticorps solute carrier family 39 member 2, anticorps solute carrier family 39 (zinc transporter), member 2, anticorps SLC39A2, anticorps Slc39a2

Sujet: The zinc transporter ZIP2, also known as SLC39A2, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of ZIP1 and ZIP3, ZIP2-null mice have no phenotypic differences compared to wild-type mice. Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient. More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adenocarcinomatous glands, and may be important in the retention of zinc in the cellular compartment.Synonyms: Eti-1, Solute carrier family 39 member 2, ZIP-2, ZIP2, Zrt- and Irt-like protein 2

ID gène: 29986

NCBI Accession: NP_055394

UniProt: Q9NP94

Pathways: Autophagy