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CDC25B anticorps (pSer149)

CDC25B Reactivité: Souris, Rat WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN871399
  • Antigène Voir toutes CDC25B Anticorps
    CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))
    Épitope
    • 27
    • 22
    • 18
    • 15
    • 15
    • 11
    • 9
    • 9
    • 8
    • 8
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer149
    Reactivité
    • 137
    • 105
    • 55
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    Souris, Rat
    Hôte
    • 185
    • 2
    Lapin
    Clonalité
    • 176
    • 11
    Polyclonal
    Conjugué
    • 72
    • 15
    • 12
    • 11
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    Cet anticorp CDC25B est non-conjugé
    Application
    • 167
    • 79
    • 52
    • 52
    • 36
    • 30
    • 14
    • 12
    • 4
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Specificité
    The antibody detects endogenous level of Cdc25B protein only when phosphorylated at serine 149.
    Purification
    Affinity purified
    Immunogène
    Peptide sequence around phosphorylation site of pSer149 (F-R-S (p) -L-P) derived from Mouse Cdc25B. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
    Top Product
    Discover our top product CDC25B Anticorps primaire
  • Indications d'application
    Western blotting: 1:500-1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Xiao, Liu, Hou, Cui, Wu, Fan, Sun, Meng, Yang, Wang, Yu: "Ser149 is another potential PKA phosphorylation target of Cdc25B in G2/M transition of fertilized mouse eggs." dans: The Journal of biological chemistry, Vol. 286, Issue 12, pp. 10356-66, (2011) (PubMed).

  • Antigène
    CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))
    Autre désignation
    Cdc25B (CDC25B Produits)
    Synonymes
    anticorps CDC25B, anticorps AI604853, anticorps cell division cycle 25B, anticorps cdc25b, anticorps CDC25B, anticorps Cdc25b
    Sujet
    Cdc25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.
    Poids moléculaire
    62 kDa
    ID gène
    12531
    NCBI Accession
    NP_001104
    UniProt
    Q9DBN8
    Pathways
    Cycle Cellulaire, M Phase, Autophagy
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