Corin anticorps (AA 165-245)

N° du produit ABIN872360

Détail du produit anti-Corin anticorps

Antigène: Corin (CORIN) (Corin, Serine Peptidase (CORIN))

Épitope: AA 165-245

Reactivité: Humain, Rat, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Corin est non-conjugé

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc))

Réactivité croisée: Humain, Rat, Mouton

Homologie: Mouse,Dog,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Corin

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-Corin (ABIN872360)

Miyazaki, Nishizawa, Kambayashi, Ito, Noda, Terasawa, Kato, Miyamura, Shiogama, Sekiya, Kurahashi, Fujii: "Increased levels of soluble corin in pre-eclampsia and fetal growth restriction." dans: Placenta, Vol. 48, pp. 20-25, (2017) (PubMed).

Sari, Rufaut, Jones, Sinclair: "Characterization of Ovine Dermal Papilla Cell Aggregation." dans: International journal of trichology, Vol. 8, Issue 3, pp. 121-9, (2016) (PubMed).

Détails sur Corin

Antigène: Corin (CORIN) (Corin, Serine Peptidase (CORIN))

Autre désignation: Corin (CORIN Produits)

Synonymes: anticorps CORIN, anticorps CG2105, anticorps Dmel\\CG2105, anticorps SP75, anticorps LOC559109, anticorps AV273130, anticorps Lrp4, anticorps ATC2, anticorps CRN, anticorps PEE5, anticorps TMPRSS10, anticorps corin, serine peptidase, anticorps CG2105 gene product from transcript CG2105-RC, anticorps novel protein similar to H.sapiens CORIN, corin, serine peptidase (CORIN), anticorps corin, anticorps CORIN, anticorps Corin, anticorps LOC559109

Sujet:

Synonyms: CRN, ATC2, Lrp4, PEE5, TMPRSS10, Atrial natriuretic peptide-converting enzyme, Corin, Heart-specific serine proteinase ATC2, Pro-ANP-converting enzyme, Transmembrane protease serine 10

Background: Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide. Isoform 2: has weaker endopeptidase activity compared to isoform 1.

ID gène: 10699

UniProt: Q9Y5Q5

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones