Myosin VIIA anticorps (AA 851-950)

N° du produit ABIN872519

Détail du produit anti-Myosin VIIA anticorps

Antigène: Myosin VIIA (MYO7A)

Épitope: AA 851-950

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Myosin VIIA est non-conjugé

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Myosin VIIa

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur Myosin VIIA

Antigène: Myosin VIIA (MYO7A)

Autre désignation: Myosin 7a (MYO7A Produits)

Synonymes: anticorps 53D10S, anticorps BG:DS00929.11, anticorps CG7595, anticorps D, anticorps D2, anticorps DM7a, anticorps DMyoVIIa, anticorps Dm 35B, anticorps DmVIIA, anticorps DmVIIa, anticorps Dmel\\CG7595, anticorps Dro35B, anticorps ESTS:53D10S, anticorps Mhc35BC, anticorps MyoVIIA, anticorps anon-35Bb, anticorps br27, anticorps ck/MyoVIIA, anticorps l(1)35Ca, anticorps l(2)07130, anticorps l(2)35Ca, anticorps l(2)br27, anticorps l35Ca, anticorps myoVIIA, anticorps stc, anticorps stch, anticorps myo7a, anticorps MYO7A, anticorps NV17859, anticorps Hdb, anticorps Myo7, anticorps USH1B, anticorps nmf371, anticorps polka, anticorps sh-1, anticorps sh1, anticorps DFNA11, anticorps DFNB2, anticorps MYOVIIA, anticorps MYU7A, anticorps NSRD2, anticorps crinkled, anticorps myosin VIIAa, anticorps myosin VIIa, anticorps myosin VIIA, anticorps myosin 7A, anticorps myosin-VIIa, anticorps ck, anticorps myo7aa, anticorps LOAG_02192, anticorps MYO7A, anticorps myo7a, anticorps LOC663995, anticorps LOC100116446, anticorps Myo7a

Sujet:

Synonyms: DFNB2, MYU7A, NSRD2, USH1B, DFNA11, MYOVIIA, Unconventional myosin-VIIa, MYO7A

Background: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. In the retina, plays an important role in the renewal of the outer photoreceptor disks. Plays an important role in the distribution and migration of retinal pigment epithelial (RPE) melanosomes and phagosomes, and in the regulation of opsin transport in retinal photoreceptors. In the inner ear, plays an important role in differentiation, morphogenesis and organization of cochlear hair cell bundles. Involved in hair-cell vesicle trafficking of aminoglycosides, which are known to induce ototoxicity (By similarity). Motor protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.

ID gène: 4647

UniProt: Q13402

Pathways: Sensory Perception of Sound