PPARGC1A anticorps (AA 151-250)

N° du produit ABIN873223

Détail du produit anti-PPARGC1A anticorps

Antigène: PPARGC1A (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha (PPARGC1A))

Épitope: AA 151-250

Reactivité: Humain, Rat, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPARGC1A est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Porc, Rat

Homologie: Mouse,Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PGC1 alpha

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur PPARGC1A

Antigène: PPARGC1A (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha (PPARGC1A))

Autre désignation: PGC1 alpha (PPARGC1A Produits)

Synonymes: anticorps PPARGC1A, anticorps PPARGC1, anticorps A830037N07Rik, anticorps ENSMUSG00000079510, anticorps Gm11133, anticorps PGC-1, anticorps PGC-1v, anticorps Pgc-1alpha, anticorps Pgc1, anticorps Pgco1, anticorps Ppargc1, anticorps PGC1, anticorps PGC1A, anticorps LEM6, anticorps PGC-1(alpha), anticorps AVPGC-1ALPHA, anticorps PPARG coactivator 1 alpha, anticorps peroxisome proliferative activated receptor, gamma, coactivator 1 alpha, anticorps PPARG coactivator 1 alpha S homeolog, anticorps PPARGC1A, anticorps Ppargc1a, anticorps ppargc1a.S

Sujet:

Synonyms: LEM6, Ligand effect modulator 6, PERC, Peroxisome prolerative activated receptor, gamma, coactivator 1 alpha, Peroxisome prolerative activated receptor, gamma, coactivator 1, Peroxisome prolerator activated receptor gamma coactivator 1 alpha, peroxisome prolerator-activated receptor gamma coactivator 1 beta, Peroxisome prolerator-activated receptor gamma coactivator 1-alpha, Peroxisome prolerator-activated receptor gamma coactivator 1-beta, peroxisome prolerator-activated receptor gamma, coactivator 1 beta, PGC 1 alpha, PGC 1 alpha, PGC 1v, PGC-1beta, PGC-1-alpha, PGC-1-beta, PGC-1-related estrogen receptor alpha coactivator, PGC1, PGC1alpha, PGC1A, PGC1v, PPAR gamma coactivator 1 alpha, PPAR gamma coactivator 1 alpha 3 ligand effect modulator 6, PPAR gamma coactivator 1, PPAR gamma coactivator variant form, PPAR gamma coactivator-1beta, PPAR-gamma coactivator 1-alpha, PPAR-gamma coactivator 1-beta, PPARGC 1 alpha, PPARGC-1-alpha, PPARGC-1-beta, PPARGC1, PPARGC1A, Ppargc1b, PRGC1_HUMAN, PRGC2_HUMAN.

Background: The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq].

Poids moléculaire: 91-110kDa

ID gène: 10891

UniProt: Q9UBK2

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Smooth Muscle Cell Migration, Brown Fat Cell Differentiation