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CCDC40 anticorps (AA 851-950) (Alexa Fluor 350)

CCDC40 Reactivité: Humain IF (cc), IF (p) Hôte: Lapin Polyclonal Alexa Fluor 350
N° du produit ABIN887705
  • Antigène Voir toutes CCDC40 Anticorps
    CCDC40 (Coiled-Coil Domain Containing 40 (CCDC40))
    Épitope
    • 14
    • 1
    AA 851-950
    Reactivité
    Humain
    Hôte
    • 15
    • 1
    Lapin
    Clonalité
    • 16
    Polyclonal
    Conjugué
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CCDC40 est conjugé à/à la Alexa Fluor 350
    Application
    • 12
    • 12
    • 4
    • 3
    • 3
    • 2
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human CCDC4
    Isotype
    IgG
    Top Product
    Discover our top product CCDC40 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    CCDC40 (Coiled-Coil Domain Containing 40 (CCDC40))
    Autre désignation
    CCDC40 (CCDC40 Produits)
    Synonymes
    anticorps CILD15, anticorps B930008I02Rik, anticorps im:7149866, anticorps lok, anticorps si:dkey-237i9.5, anticorps wu:fb11d02, anticorps coiled-coil domain containing 40, anticorps CCDC40, anticorps Ccdc40, anticorps ccdc40
    Sujet

    Synonyms: CCD40_HUMAN, ccdc 40, CCDC40, Coiled coil domain containing 40, coiled-coil domain containing 40, Coiled-coil domain-containing protein 40.

    Background: Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Not required for outer dynein arm complexes assembly. Required for axonemal recruitment of CCDC39.Involvement in disease:Defects in CCDC40 are the cause of primary ciliary dyskinesia type 15 (CILD15) . A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia, reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome.

    ID gène
    55036
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