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KRT12 anticorps (AA 151-250) (Alexa Fluor 647)

KRT12 Reactivité: Humain, Souris WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Alexa Fluor 647
N° du produit ABIN890816
  • Antigène Voir toutes KRT12 Anticorps
    KRT12 (Keratin 12 (KRT12))
    Épitope
    • 14
    • 13
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 151-250
    Reactivité
    • 42
    • 19
    • 8
    • 1
    • 1
    Humain, Souris
    Hôte
    • 45
    • 2
    • 1
    Lapin
    Clonalité
    • 47
    • 1
    Polyclonal
    Conjugué
    • 19
    • 7
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp KRT12 est conjugé à/à la Alexa Fluor 647
    Application
    • 41
    • 21
    • 17
    • 13
    • 12
    • 12
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Souris, Rat
    Homologie
    Dog,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human CK12/Cytokeratin 12
    Isotype
    IgG
    Top Product
    Discover our top product KRT12 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    KRT12 (Keratin 12 (KRT12))
    Autre désignation
    CK12 (KRT12 Produits)
    Synonymes
    anticorps fb05e09, anticorps wu:fa91b04, anticorps wu:fa97a07, anticorps wu:fb05e09, anticorps k12, anticorps xk81b2, anticorps K12, anticorps AI835216, anticorps Krt-12, anticorps Krt1-12, anticorps Ka12, anticorps keratin 91, anticorps keratin 12, anticorps keratin 12 S homeolog, anticorps krt91, anticorps KRT12, anticorps krt12, anticorps Krt12, anticorps krt12.S
    Sujet

    Synonyms: 65 kDa cytokeratin, CK 12, CK 3, CK12, CK3, Cytokeratin 12, Cytokeratin 3, K12, K3, keratin 12 Meesmann corneal dystrophy, Keratin 12, Keratin 3, Keratin, type I cytoskeletal 12, K1C12_HUMAN, Keratin, type II cytoskeletal 3, KRT12, KRT3.

    Background: Cytokeratin 12 is a member of the intermediate filament family of proteins and is a heterotetramer of two type I and two type II keratins. Keratin 3 is specifically expressed in the corneal epithelium with family member KRT12. Cytokeratin 12 encodes the type I intermediate filament chain keratin 12, expressed in corneal epithelia. Defects in KRT3 and KRT12 are a cause of Meesmann corneal dystrophy (MCD), an autosomal dominant disease that causes fragility of the anterior corneal epithelium. Symptoms occur in adulthood and include rupture of the corneal microcysts that may lead to photophobia, contact lens intolerance and intermittent diminution of visual acuity. Defects in KRT12 are a cause of juvenile epithelial corneal dystrophy of Meesmann (MCD)

    Poids moléculaire
    54kDa
    ID gène
    3859
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