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FAM21C anticorps (AA 1201-1318) (Alexa Fluor 350)

FAM21C Reactivité: Rat IF (cc), IF (p) Hôte: Lapin Polyclonal Alexa Fluor 350
N° du produit ABIN896484
  • Antigène Voir toutes FAM21C Anticorps
    FAM21C (Family with Sequence Similarity 21, Member C (FAM21C))
    Épitope
    • 14
    • 2
    AA 1201-1318
    Reactivité
    • 14
    • 2
    Rat
    Hôte
    • 14
    • 2
    Lapin
    Clonalité
    • 16
    Polyclonal
    Conjugué
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FAM21C est conjugé à/à la Alexa Fluor 350
    Application
    • 12
    • 12
    • 3
    • 3
    • 3
    • 2
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Rat
    Homologie
    Human,Mouse,Cow,Pig,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human FAM21C
    Isotype
    IgG
    Top Product
    Discover our top product FAM21C Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    FAM21C (Family with Sequence Similarity 21, Member C (FAM21C))
    Autre désignation
    FAM21C (FAM21C Produits)
    Synonymes
    anticorps Fam21, anticorps NP61201, anticorps FAM21A, anticorps VPEF, anticorps A130095H06, anticorps C530005J20Rik, anticorps D6Wsu116e, anticorps fam21c, anticorps wu:fb78c06, anticorps zgc:153646, anticorps WASH complex subunit 2C, anticorps WASH complex subunit 2, anticorps family with sequence similarity 21, member C, anticorps Washc2c, anticorps WASHC2C, anticorps Washc2, anticorps washc2c
    Sujet

    Synonyms: FAM21A, Family with sequence similarity 21 member C, Hypothetical protein LOC253725, KIAA0592, Protein FAM21C, FA21C_HUMAN.

    Background: Playing a essential role in the fission of tubules that serve as transport intermediates during endosome sorting, the WASH complex is present at the surface of endosomes and functions to recruit and activate the Arp2/3 complex for induction of actin polymerization. FAM21, Putative WASH complex subunit FAM21, is a component of the WASH complex. Having undergone evolutionary duplication, four highly homologous family members exist including FAM21A, FAM21B, FAM21C and FAM21D. FAM21 links the WASH complex to endosomes and is required for WASM-dependent retromer-mediated sorting. Also, by directly interacting with CapZ, FAM21 inhibits its anti-capping activity, thereby regulating actin dynamics.

    ID gène
    253725
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